Validation of the ‘Polymorphic Light Eruption Severity Index’

Randomized double-blinded placebo-controlled intra-individual trial on topical treatment with a 1,25-dihydroxyvitamin D3 analogue in polymorphic light eruption

“…Indeed, this is evidenced by the results of Table 1, containing the number of PLE events, and that of Table 2, showing more positive score values than PLE events, a difference attributed to the incorporation of pruritus into the score. Other investigators have previously established different scores to grade the severity of PLE based on questions concerning the occurrence of the skin rash and quality of life during spring and summer months 38–43 . For instance, Palmer et al.…”

“…For instance, Palmer et al. 38,39 have validated their PLE severity index (i.e. PLESI) and established a mathematical equation with a sigmoid curve describing the link of the PLESI score to the probability of successful photoprovocation.…”

The quality of life of 790 patients with photodermatoses

“…Palmer et al. proposed PLESI to be used to assess the severity of PLE; 12 a high index was found to be associated with the likelihood of positive experimental disease provocation with solar‐simulated radiation in a small group of patients. The index was derived from a standardized interview using 10 questions based on patient recall of PLE‐related events over the last 12 months.…”

Skin hardening effect in patients with polymorphic light eruption: Comparison of UVB hardening in hospital with a novel home UV‐hardening device

“…Patients also filled in under supervision the Polymorphic Light Eruption Severity Index (PLESI) form. This is a standardized interview that provides an assessment of PLE gravity on scale 2–100 7,8 . After the hardening, patients were asked to fill in the DLQI questionnaire once more.…”

“…This is a standardized interview that provides an assessment of PLE gravity on scale 2-100. 7,8 After the hardening, patients were asked to fill in the DLQI questionnaire once more. Two months after hardening (during the summer), patients were asked about their own experience with the hardening and its effect on the subsequent development of PLE.…”