Background
The Mangled Extremity Severity Score (MESS) was developed 25 years
ago in an attempt to utilize the extent of skeletal and soft tissue injury,
limb ischemia, shock, and age to predict the need for amputation after
extremity injury. Subsequently, there have been mixed reviews as to the
utility of this score. We hypothesized that the MESS, when applied to a data
set collected prospectively in modern times, would not correlate with the
need for amputation.
Methods
We applied the MESS to patient data collected in the American
Association for the Surgery of Trauma PROspective Vascular Injury Treatment
(PROOVIT) registry. This registry contains prospectively collected
demographic, diagnostic, treatment, and outcome data.
Results
Between 2013 and 2015, 230 patients with lower extremity arterial
injuries were entered into the PROOVIT registry. The majority were male with
a mean age of 34 years (range 4–92) and a blunt mechanism of injury
at a rate of 47.4%. A MESS of 8 or greater was associated with a
longer stay in the hospital (median 22.5 (15, 29) vs 12 (6, 21), p=0.006)
and ICU (median 6 (2, 13) vs 3 (1, 6), p=0.03). 81.3% of limbs were
ultimately salvaged (median MESS 4 (3, 5)) and 18.7% required
primary or secondary amputation (median MESS 6 (4, 8), p < 0.001).
However, after controlling for confounding variables including mechanism of
injury, degree of arterial injury, injury severity score, arterial location,
and concomitant injuries, the MESS between salvaged and amputated limbs was
no longer significantly different. Importantly, a MESS of 8 predicted
in-hospital amputation in only 43.2% of patients.
Conclusion
Therapeutic advances in the treatment of vascular, orthopedic,
neurologic and soft tissue injuries have reduced the diagnostic accuracy of
the MESS in predicting the need for amputation. There remains a significant
need to examine additional predictors of amputation following severe
extremity injury.
Level of Evidence
Level III evidence, prospective study, prognostic.