Validation of the Thermodilution Technique for the Estimation of the Cardiac Output in the Unsedated Calf

Amory, Hélène; Lindén, Annick; Desmecht, Daniël; Génicot, Bruno; Lekeux, Pierre

doi:10.1111/j.1439-0442.1991.tb01029.x

Cited by 9 publications

(11 citation statements)

References 32 publications

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“…When this was studied, the reproducibility was tested on successive (most often, duplicate or triplicate) measures, performed at only a few minutes' interval (Amory et al, 1991). The purpose of such studies was to validate the cardiac output measurement by the thermodilution technique, by comparing its reproducibility with other pre-existing techniques.…”

Section: Discussionmentioning

confidence: 99%

“…This catheter was used to measure the central venous pressure and to inject the bolus for cardiac output determination. The cardiac output was measured by a cardiac output thermodilution computer (Cardiomax II, Columbus Instruments) as previously described (Amory et al, 1991). Five to ten successive measurements were performed and averaged.…”

Section: Measurementsmentioning

confidence: 99%

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Technical and methodological requirements for reliable haemodynamic measurements in the unsedated calf

et al. 1992

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The purpose of this study was (1) to evaluate the technical and methodological problems associated with invasive haemodynamic measurements in unsedated cattle; (2) to assess the reproducibility of such measurements both within and between days; and (3) to compare the values with those previously reported. Twenty-one healthy calves, aged from 5.5 to 12 months, were studied. The central venous, the right ventricular, the pulmonary arterial, the pulmonary capillary wedge and the systemic arterial pressures were obtained by means of fluid-filled catheters, and the cardiac output was measured by the thermodilution technique. The heart rate, the stroke volume, the pulmonary and systemic vascular resistances and the pulmonary and systemic ventricular workloads were calculated. An adverse reaction, consisting of severe pulmonary hypertension, tachycardia, tachypnoea and transient weakness, occurred in 7 calves during the catheterization procedures. Such a reaction might be due to a local reflex induced by stimulation of mechano-receptors by the catheter tip. It should be avoided by reducing the manipulation of the catheter as much as possible and by inflating the tip of the balloon when moving it forwards. A comparison of the vascular pressures with those previously reported was difficult because of methodological or technical limitations, such as, for instance, a lack of standardization of the baseline. The reproducibility of the haemodynamic measurements obtained was satisfactory, in contrast to previous studies performed in conscious animals. This was attributed to our animals being better trained to the experimental conditions and emphasizes the importance of reducing mental stress in obtaining reliable haemodynamic measurements in unsedated and potentially uncooperative animals.

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Section: Discussionmentioning

confidence: 99%

Section: Measurementsmentioning

confidence: 99%

Technical and methodological requirements for reliable haemodynamic measurements in the unsedated calf

et al. 1992

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“…The awake state is known to induce greater variability in

\dot{normalQ} t

measurements (Amory et al. ). The fact that calves objected to the injection of 10 mL of cold indicator may possibly explain why we needed to perform an unusually high number of injections to obtain three PATD measurements within ± 10%.…”

Section: Discussionmentioning

confidence: 99%

“…Pulmonary artery thermodilution (PATD) as a technique to measure

\dot{normalQ} t

has been evaluated in the unsedated calf using the Fick method as a reference method (Amory et al. ). Both PATD and the Fick method require the placement of a pulmonary artery catheter (PAC), which has been found to lead to an unusually high prevalence of ventricular dysrhythmias and pulmonary hypertension in cattle compared with other species (Reeves & Leathers ; Amory et al.…”

Section: Introductionmentioning

confidence: 99%

Comparison of pulmonary artery and transpulmonary thermodilution cardiac output measurements in unsedated newborn calves

Kutter

Schefer

Bircher

et al. 2015

Veterinary Anaesthesia and Analgesia

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“…Cardiac output (CO) was measured by the thermodilution technique as previously described (Amory et al 1991). Briefly, a 7F balloontipped triple-lumen Swan-Ganz catheter (Elecath 73-4067 7F, Columbus Instruments, Columbus, Ohio) was advanced under pressuretracing monitoring from the cervical jugular vein into the pulmonary artery, which allowed pulmonary arterial temperature to be measured.…”

Section: Flow Measurementsmentioning

confidence: 99%

Hemodynamic responses to Pasteurella haemolytica inoculation in calves given type 2 serotonergic antagonist

Desmecht¹,

Lindén²,

Amory³

et al. 1996

Can. J. Physiol. Pharmacol.

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The effects of saline (control, group C) and metrenperone (treated, group M) on systemic and pulmonary hemodynamics were determined in conscious 7- to 15-day-old calves after they were intratracheally inoculated with Pasteurella haemolytica. Metrenperone, a specific serotonin (5-hydroxytryptamine) receptor antagonist, was injected intramuscularly (100 micrograms.kg-1) 2 h after the calves were inoculated. Central venous, pulmonary arterial and capillary wedge, and systemic arterial pressures were measured, using fluid-filled catheters. Cardiac output was measured by the thermodilution technique. Heart rate, stroke volume, and pulmonary and systemic vascular resistances were calculated. The parameters were measured hourly from the 1st to the 10th h after inoculation. In group C, cardiovascular response to P. haemolytica inoculation was marked and typically consisted of two systemic hypotensive phases and two pulmonary hypertensive phases. The first phase occurred by the 2nd h post inoculation and was induced by a transient bradycardia and a systemic vasodilation, leading to profound hypotension and reduced venous return. Cardiac performance then transiently recovered, but systemic hypotension persisted. The second hypotensive hypodynamic phase occurred by the 7th h after inoculation, and was associated with a decline in stroke volume, an increase in heart rate, and pulmonary hypertension and vasoconstriction. In group M, the early response to P. haemolytica exposure was similar to that in controls, indicating that, as in sheep, 5-hydroxytryptamine does not contribute to the early hypodynamic response to endotoxemia. In contrast, metrenperone completely abolished late increases in pulmonary arterial pressure and pulmonary vascular resistance, suggesting that 5-hydroxytryptamine contributes to the late pulmonary vasoconstriction. Metrenperone treatment also allowed better restoration of heart rate, and hence, cardiac output was maintained. In conclusion, 5-hydroxytryptamine might have a role in mediating pasteurellic endotoxin induced changes in pulmonary hemodynamics through its type-2 receptors.

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Validation of the Thermodilution Technique for the Estimation of the Cardiac Output in the Unsedated Calf

Cited by 9 publications

References 32 publications

Technical and methodological requirements for reliable haemodynamic measurements in the unsedated calf

Technical and methodological requirements for reliable haemodynamic measurements in the unsedated calf

Comparison of pulmonary artery and transpulmonary thermodilution cardiac output measurements in unsedated newborn calves

Hemodynamic responses to Pasteurella haemolytica inoculation in calves given type 2 serotonergic antagonist

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