Validation of the UICC 8th edition staging of oral cavity squamous cell carcinoma in a UK cohort

McGoldrick, David; Torres-Rendon, A.; Sandhu, Raj; Walton, Gary M.

doi:10.1016/j.bjoms.2020.08.029

Cited by 2 publications

(1 citation statement)

References 13 publications

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“…From the initial 778 articles identified by the electronic search, 36 studies were selected for full-text assessment. Of these, 23 studies ( 12 - 34 ) were excluded due to the reasons shown in the flowchart (Fig. 1 ), which reflects the selection process of the studies during the systematic review.…”

Section: Resultsmentioning

confidence: 99%

Has the 8th American joint committee on cancer TNM staging improved prognostic performance in oral cancer? A systematic review

Erazo-Puentes,

Sánchez-Torres,

Aguirre-Urizar

et al. 2024

Med Oral

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Background The 8th edition of the American Joint Committee on Cancer (AJCC) classification has introduced two new parameters: depth of invasion (DOI) and extranodal extension (ENE). The aim of this systematic review was to determine whether this 8th edition referred to oral squamous cell carcinoma (OSCC) offers performance superior to that of the 7th edition in relation to overall survival (OS) and disease-specific survival (DSS). Material and Methods The review was carried out following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses) guidelines. The PubMed (MEDLINE), Scopus and Cochrane Library databases were searched covering the period up until April 7th, 2022. Results Thirteen retrospective cohort studies were finally included. The introduction of DOI and ENE in the 8th edition of the AJCC classification resulted in improved prognostic performance of the classification. Conclusions Patients with OSCC can be better classified in relation to OS and DSS, while maintaining the simplicity and ease of use of the classification. This allows more appropriate treatment protocols to be applied and affords a better estimation of the prognosis of each patient. Key words: TMN Staging, AJCC8, squamous cell carcinoma, oral cancer, prognosis.

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Section: Resultsmentioning

confidence: 99%