“…On the other hand, Thomas et (8). In the study of Gardin et al (6) and in the present study, the subjects included higher age persons than in the study of Thomas et (12). Therefore, LAWV may be used as a tool for evaluating the characteristics of active LA contraction.…”
Section: F I G U R E 4 Ag E P L O T T E D a G A I N S T L E F T A Tmentioning
“…On the other hand, Thomas et (8). In the study of Gardin et al (6) and in the present study, the subjects included higher age persons than in the study of Thomas et (12). Therefore, LAWV may be used as a tool for evaluating the characteristics of active LA contraction.…”
Section: F I G U R E 4 Ag E P L O T T E D a G A I N S T L E F T A Tmentioning
“…Next, we examined the LA contractility in patients with heart failure. We have previously reported that LAWV is correlated with the flow velocity in the LA appendage or with the fractional shortening of the LA appendage; this indicates that LAWV is an indicator of LA contractile performance 10 . Several researchers have described the role of LA contractility in active LA emptying.…”
Section: Discussionmentioning
confidence: 86%
“…LAWV was measured in the apical three‐chamber view by using pulsed tissue Doppler echocardiography; this value was represented as a velocity profile. We used an M3S probe with a frequency of 1.7/3.4 MHz, an acoustic pressure setting of 0 dB, a frame rate of 142 frames/s, and a sampling volume of 8 mm in height and 4 mm in width 10,15,16 …”
Section: Methodsmentioning
confidence: 99%
“…We considered that the former ROI was appropriate for measuring LAWV, because the posterobasal LA wall motion was not affected by the adjacent structures, such as the left ventricle or aortic root. Moreover, the LA wall motion vector of this area is considered to be nearly parallel to the ultrasonic beam from the apical view 10,15,16 …”
Section: Methodsmentioning
confidence: 99%
“…Similar to the ventricular wall contraction velocity, the LA wall contraction velocity (LAWV) may be an indicator of LA contractility during atrial contraction. We have previously reported that LAWV correlates with the LA appendage flow velocity or fractional shortening; this finding suggests that LAWV is a marker of LA contractile function 10 . The role of LAWV in LA emptying has been studied using tissue Doppler echocardiography in patients with hypertrophic cardiomyopathy 11 .…”
The aim of this study was to investigate the role and limitations of left atrial (LA) preload or contractility as determinants of active LA emptying in patients with heart failure. In 56 healthy individuals (controls) and 30 patients with heart failure, the LA volume before atrial contraction (LAV(pre) I), the LA volume reduction (LASVI) and LA wall contraction velocity (LAWV) during atrial contraction, and the transmitral peak flow velocities during early diastole (E) and atrial contraction (A) were determined using two-dimensional pulsed Doppler or tissue Doppler echocardiography. LAV(pre) I and LASVI were positively correlated in patients whose A/E ratio was ≥1 (r = 0.58) and negatively correlated in those whose A/E ratio was <1 (r =-0.63). LAWV was significantly lower in those with heart failure than in the controls 2.2 (1.2) cm/sec, versus 3.3 (0.8) cm/sec; mean (standard deviation) and negatively correlated with left ventricular end-diastolic pressure (r =-0.37). LAWV and LASVI were significantly correlated (r = 0.71). This correlation was stronger in the patients whose A/E ratio was <1 than in those whose A/E ratio was ≥1. Multivariate regression analysis showed that LAWV was the only factor affecting LASVI. In patients with heart failure and an A/E ratio of <1, the contribution of LA dilatation to active LA emptying may be limited, and LAWV may be the most important determinant of active LA emptying, even if this velocity is decreased because of elevated left ventricular diastolic pressure.
Acquiring and quantifying LAA A(M) contraction velocity is feasible on TTE in a high percentage of patients and correlates with TEE. LAA A(M) was lower in AF compared with sinus rhythm, with spontaneous echo contrast compared to without spontaneous echo contrast, and in AF patients with a history of stroke or TIA. Those with LAA thrombus had the lowest LAA A(M) velocities. LAA A(M) is a novel functional parameter that may prove useful for risk stratification of AF.
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