Validity and reliability of the CAPE: a self‐report instrument for the measurement of psychotic experiences in the general population

Konings, M.; Bak, Maarten; Hanssen, M.S.S.; Os, Jim van; Krabbendam, Lydia

doi:10.1111/j.1600-0447.2005.00741.x

Cited by 462 publications

(379 citation statements)

References 42 publications

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“…The CAPE is a self-report instrument and captures variation in the positive and negative dimensions of nonclinical psychotic experiences as well as variation in depression. This scale was recently validated against clinical interview measures of schizotypy and psychosis-proneness (Konings et al, 2006). Previous work has shown that subclinical psychotic experiences measured with valid self-report questionnaires show longitudinal continuity with more severe states of psychosis, such as psychotic illness (Chapman et al, 1994;Hanssen et al, 2005) and are transmitted in families .…”

Section: Psychosis Measuresmentioning

confidence: 99%

An Experimental Study of Catechol-O-Methyltransferase Val158Met Moderation of Δ-9-Tetrahydrocannabinol-Induced Effects on Psychosis and Cognition

Henquet

Rosa

Krabbendam

et al. 2006

Neuropsychopharmacol

286

210

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Observational studies have suggested that psychometric psychosis liability and a functional polymorphism in the catechol-Omethyltransferase (COMT Val 158 Met) gene moderate the psychosis-inducing effect of cannabis. To replicate and extend this finding, a double-blind, placebo-controlled cross-over design was used in which patients with a psychotic disorder (n ¼ 30), relatives of patients with a psychotic disorder (n ¼ 12), and healthy controls (n ¼ 32) were exposed to D-9-tetrahydrocannabinol (D-9-THC, the principal component of cannabis) or placebo, followed by cognitive assessment and assessment of current psychotic experiences. Previous expression of psychometric psychosis liability was also assessed. Models of current psychotic experiences and cognition were examined with multilevel random regression analyses to assess (i) main effects of genotype and condition, (ii) interactions between condition and genotype, and (iii) three-way interactions between condition, genotype, and psychometric psychosis liability. Carriers of the Val allele were most sensitive to D-9-THC-induced psychotic experiences, but this was conditional on prior evidence of psychometric psychosis liability. D-9-THC impacted negatively on cognitive measures. Carriers of the Val allele were also more sensitive to D-9-THC-induced memory and attention impairments compared to carriers of the Met allele. Experimental effects of D-9-THC on cognition and psychosis are moderated by COMT Val 158 Met genotype, but the effects may in part be conditional on the additional presence of pre-existing psychosis liability. The association between cannabis and psychosis may represent higher order gene-environment and gene-gene interactions.

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Section: Psychosis Measuresmentioning

confidence: 99%

An Experimental Study of Catechol-O-Methyltransferase Val158Met Moderation of Δ-9-Tetrahydrocannabinol-Induced Effects on Psychosis and Cognition

Henquet

Rosa

Krabbendam

et al. 2006

Neuropsychopharmacol

286

210

View full text Add to dashboard Cite

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“…The positive dimension of the CAPE (18 self-report items), based on the Peters et al Delusions Inventory (Peters et al 1999) and modified to also include hallucinatory experiences, was used to assess lifetime subclinical positive psychotic experiences (Stefanis et al 2002;Konings et al 2006). Each CAPE item rates the frequency of subclinical psychotic experiences on a four-point scale; scores can thus range from 18 to 72, and higher scores indicate more subclinical psychotic experiences.…”

Section: Instrumentsmentioning

confidence: 99%

Subclinical psychotic experiences and bipolar spectrum features in depression: association with outcome of psychotherapy

Wigman

Abidi

et al. 2013

Psychol. Med.

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Background. Subthreshold psychotic and bipolar experiences are common in major depressive disorder (MDD). However, it is unknown if effectiveness of psychotherapy is altered in depressed patients who display such features compared with those without. The current paper aimed to investigate the impact of the co-presence of subclinical psychotic experiences and subclinical bipolar symptoms on the effectiveness of psychological treatment, alone or in combination with pharmacotherapy.Method. In a naturalistic study, patients with MDD (n = 116) received psychological treatment (cognitive behavioural therapy or interpersonal psychotherapy) alone or in combination with pharmacotherapy. Depression and functioning were assessed six times over 2 years. Lifetime psychotic experiences and bipolar symptoms were assessed at the second time point.Results. Subclinical psychotic experiences predicted more depression over time (β = 0.20, p < 0.002), non-remission [odds ratio (OR) 7.51, p < 0.016] and relapse (OR 3.85, p < 0.034). Subthreshold bipolar symptoms predicted relapse (OR 1.16, p < 0.037).Conclusions. In general, subclinical psychotic experiences have a negative impact on the course and outcome of psychotherapy in MDD. Effects of subclinical bipolar experiences were less prominent.

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“…low mood and negative cognitions). The CAPE has been validated in clinical and non-clinical samples and found to reliably assess positive, negative and depressive symptoms (Hanssen et al, 2003; Konings, Bak, Hanssen, Van Os, & Krabbendam, 2006). …”

Section: Methodsmentioning

confidence: 99%

The Trauma and Life Events (TALE) checklist: development of a tool for improving routine screening in people with psychosis

Carr

Hardy

Fornells-Ambrojo

2018

European Journal of Psychotraumatology

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Background: Best practice guidelines recommend traumatic events should be assessed in psychosis to support the identification and, when indicated, treatment of post-traumatic stress reactions. However, routine assessment in frontline services is rare, and available tools are not tailored to psychosis. Assessment obstacles include lengthy measures, a focus on single, physically threatening events, and the exclusion of psychosis-related traumas. Objective: To develop and validate a brief trauma screening tool for the identification of clinically significant traumas in people with psychosis. Method: The Trauma and Life Events (TALE) checklist was developed in conjunction with people with lived experience of trauma and psychosis, and specialist clinicians and researchers. The psychometric properties (i.e. test-retest reliability, content validity, construct validity) of the TALE were evaluated in a sample of 39 people with psychosis diagnoses. Results: The TALE displayed moderate psychometric acceptability overall, with excellent reliability and convergent validity for sexual abuse. High rates of psychosis-related trauma and childhood adversity were reported, in particular bullying and emotional neglect. A dose–response relationship between cumulative trauma, post-traumatic stress and psychosis was found. Conclusions: The TALE is the first screening tool specifically designed to meet the needs of routine trauma screening in psychosis services. The psychometric limitations highlight the challenge of developing a measure that is both sufficiently brief to be useful in clinical settings and comprehensive enough to identify all relevant adverse events. Validation of the TALE is now required across the spectrum of psychosis.

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Validity and reliability of the CAPE: a self‐report instrument for the measurement of psychotic experiences in the general population

Abstract: The results indicate that self-reported dimensions of psychotic experiences in general population samples appear to be stable, reliable and valid.

Cited by 462 publications

References 42 publications

An Experimental Study of Catechol-O-Methyltransferase Val158Met Moderation of Δ-9-Tetrahydrocannabinol-Induced Effects on Psychosis and Cognition

An Experimental Study of Catechol-O-Methyltransferase Val158Met Moderation of Δ-9-Tetrahydrocannabinol-Induced Effects on Psychosis and Cognition

Subclinical psychotic experiences and bipolar spectrum features in depression: association with outcome of psychotherapy

The Trauma and Life Events (TALE) checklist: development of a tool for improving routine screening in people with psychosis

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