Validity and reliability of the 13C-methionine breath test for the detection of moderate hyperhomocysteinemia in Mexican adults; statistical issues in validity and reliability analysis

Reliability of the International Spinal Cord Injury Musculoskeletal Basic Data Set; methodological and statistical issue to avoid misinterpretation

“…In other words, possibility of getting exactly the same crude agreement of a variable between methods with no reliability at all is high. 2,3,9 As the authors pointed out in their conclusion, overall, the ISCIMSBDS is reliable. Such conclusions may be a misleading message due to inappropriate use of statistical tests.…”

“…1 Regarding reliability, it is crucial to know that an individual-based approach instead of group-based (crude agreement) should be considered. [2][3][4][5][6][7][8][9] The reason is in reliability assessment; we should consider individual results and not global average. In other words, possibility of getting exactly the same crude agreement of a variable between methods with no reliability at all is high.…”

Improved Outcomes When Antibiotic Prescribing Guidelines Are Followed by Healthcare Providers: A Colombian Example to Encourage Adherence in Hospital Settings

“…[6][7][8][9][10] It is crucial to know that to assess validity, sensitivity, specificity,) positive predictive value (PPV), negative predictive value (NPV), the most appropriate tests are likelihood ratio positive and likelihood ratio negative as well as diagnostic accuracy and odds ratio. [6][7][8][9][10] Kerlin et al concluded that prospective surveillance using VAE criteria is more reliable than traditional VAP surveillance and clinical VAP diagnosis; the correlation between VAEs and clinically recognized pulmonary deterioration is poor. Such a conclusion may be misleading due to the inappropriate use of a statistical test to assess reliability and validity.…”

Etest to detect drug-resistant Neisseria gonorrhoeae to contemporary treatment; methodological issues concerning accuracy and reproducibility

“…In the case of quantitative variables, depending on the distribution of the variable, the Pearson r or Spearman rho can be applied. Therefore, to assess reproducibility and accuracy, appropriate tests as well as correct interpretations should be considered [2][3][4][5].In this letter, I emphasized methodological and statistical issues in reproducibility and accuracy analysis. Papp and colleagues concluded that the Etest method yielded reproducible MIC values within each laboratory, with the azithromycin and ceftriaxone MIC results being consistent with the reference agar dilution method.…”

“…In the case of quantitative variables, depending on the distribution of the variable, the Pearson r or Spearman rho can be applied. Therefore, to assess reproducibility and accuracy, appropriate tests as well as correct interpretations should be considered [2][3][4][5].…”