Objective: To validate a brief FFQ developed for capturing short-term antioxidant intake in a sample of US college students. Design: A seventy-four-item antioxidant FFQ was developed based on major antioxidant sources in the American diet. The FFQ was validated against 30 d food records (FR) and plasma antioxidant concentrations. The reliability of the FFQ was evaluated by two FFQ administered at a 1-month interval. Settings: University of Connecticut, CT, USA. Subjects: Sixty healthy college students. Results: Estimates of dietary antioxidants from the FFQ were moderately to highly correlated with those estimated from the 30 d FR (r 5 0?29-0?80; P , 0?05) except for g-tocopherol and b-cryptoxanthin. Total antioxidant capacity from diet only or from diet and supplements estimated by the 30 d FR and FFQ were highly correlated (r 5 0?67 and 0?71, respectively; P , 0?0001). The FFQ categorized 91 % of participants into the same or adjacent tertiles of antioxidant intake as the 30 d FR. Most dietary carotenoids estimated from the FFQ were correlated with plasma levels (P , 0?05). Correlation coefficients for test-retest reliability ranged from 0?39 to 0?86. More than 94 % of the participants were classified in the same or adjacent tertiles between the two administrations of the FFQ.
Conclusions:The brief FFQ demonstrated reasonable validity for capturing a comprehensive antioxidant intake profile. This FFQ is applicable in epidemiological or clinical studies to capture short-term antioxidant intake or to simply document the variations of antioxidant intake in intervention trials. Cross-validation studies are warranted in other target populations.