Validity and Reproducibility of Determination of Cardiac Output by Thermodilution in Man

Olsson, Bertil; Pool, J M; Vandermoten, P; Varnauskas, E; Wassén, R

doi:10.1159/000169277

Cited by 76 publications

(28 citation statements)

References 11 publications

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“…However, in clinical settings, CO determination using the Fick method appears to be superior to the thermodilution technique in the presence of tricuspid regurgitation. 10,43,136 Aortic or mitral regurgitation may render the indicator dilution technique inaccurate. 115,~38-140 Distortion of the dye dilution curves by coronary recirculation in patients with severe aortic or mitral regurgitation 138 may be alleviated by sampling dye in the right heart.…”

Section: Valvular Heart Diseasesmentioning

confidence: 99%

Errors in the measurement of cardiac output by thermodilution

1993

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Section: Valvular Heart Diseasesmentioning

confidence: 99%

Errors in the measurement of cardiac output by thermodilution

1993

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“…Thermodilution. Cardiac output estimation was performed by a trained ICU registered nurse in standardized fashion, 14 using the rapid injection of 5 mL of iced saline 15 through the proximal port of the catheter at end-expiration, just before taking a breath. Cardiac output was then calculated by the computer (Hewlett Packard, Mississauga, Ontario, Canada), and only waveforms acceptable to the nurse were used for calculation.…”

Section: Methodsmentioning

confidence: 99%

Improving the Accuracy of Impedance Cardiac Output in the Intensive Care Unit: Comparison With Thermodilution Cardiac Output

Fuller

2006

Congestive Heart Failure

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This study examined the effect of impedance algorithm adjustment to reflect abnormalities found in cardiac output estimation in the intensive care unit. Impedance (Kubicek and Sramek equations) and thermodilution were measured concurrently in 61 patients. The mean difference between Kubicek and thermodilution (n=40) was 1.47 L/min (95% confidence interval [CI], 0.47–2.47) and between Sramek and thermodilution (n=54) was 2.68 L/min (95% CI, 1.93–3.44). Exclusion of patients with valve regurgitation improved agreement between Kubicek and thermodilution (n=32), with a mean difference of 2.02 L/min (95% CI, 1.10–2.94). Multiple regression determined the role of skinfold thickness, pH, hematocrit, sodium, chloride, albumin, protein, and urea within impedance. Kubicek was recalculated using the new algorithm and recompared with thermodilution. The mean difference was −0.38 L/min (95% CI, −1.92 to 1.16). This study found poor agreement between impedance and thermodilution in critically ill patients, but exclusion of those with valve regurgitation and adjustment for hematocrit and skinfold thickness improved agreement.

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“…The reference level was 5 cm below the sternal insertion of the fourth rib. Cardiac output was measured by a double thermistor technique (17). Saline was injected in the superior vena cava and the temperature was measured at the site of injection and in the main pulmonary artery.…”

Section: Methodsmentioning

confidence: 99%

Hemodynamic Effects of Combined Treatment with Lignocaine, Procainamide and Practolol in Acute Myocardial Infarction

Nordlander¹,

Nyquist²

1980

Cardiology

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In the treatment of refractory ventricular tachyarrhythmias antiarrhythmic drugs must sometimes be combined. An electrophysiologically appropriate combination is lignocaine and procainamide and, when needed, a β-blocking agent. The hemodynamic effects of this treatment were studied in 6 patients in the acute phase of myocardial infarction. After a control period, an infusion of lignocaine was started and 1 h later procainamide/placebo was added in a double-blind system and finally also practolol/placebo. The drugs were given intravenously in ordinary doses. Hemodynamics were studied by bedside catheterization. During triple treatment heart rate and aortic pressures fell significantly whereas right atrial mean pressure increased compared to the control period. Stroke volume, cardiac output and pulmonary artery pressures were unchanged. Most of the changes appeared when practolol was added. Following the procainamide injection a transient fall in aortic pressures was noted. Lignocaine gave no hemodynamic effects. The number of ventricular premature beats was reduced in all patients and no patient had ventricular tachycardia during treatment. In these patients it was possible to combine lignocaine, procainamide and practolol in the acute phase of myocardial infarction. However, 3 patients developed hypotension, 1 sinus bradycardia and 1 had a short run of nodal tachycardia. It is concluded that this kind of combined treatment, because of its potential risks, should be restricted to critical clinical situations and then it ought to be hemodynamically controlled.

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Validity and Reproducibility of Determination of Cardiac Output by Thermodilution in Man

Cited by 76 publications

References 11 publications

Errors in the measurement of cardiac output by thermodilution

Errors in the measurement of cardiac output by thermodilution

Improving the Accuracy of Impedance Cardiac Output in the Intensive Care Unit: Comparison With Thermodilution Cardiac Output

Hemodynamic Effects of Combined Treatment with Lignocaine, Procainamide and Practolol in Acute Myocardial Infarction

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