Validity of Adjuvant! Online program in older patients with breast cancer: a population-based study

Glas, Nienke A. de; Water, W. van de; Engelhardt, Ellen G.; Bastiaannet, E.; Craen, Anton J. M. de; Kroep, Judith R.; Putter, Hein; Stiggelbout, Anne M.; Weijl, N.I.; Velde, Cornelis J.H. van de; Portielje, Johanneke E.A.; Liefers, Gerrit‐Jan

doi:10.1016/s1470-2045(14)70200-1

Cited by 82 publications

(52 citation statements)

References 30 publications

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“…Adjuvant! Online, despite taking into account the comorbidities, did not accurately predict OS and recurrence [47] while PREDICT can only accurately predict 5-year but not 10-year OS in older patients with EBC [48].…”

Section: Triple Negative Ebcmentioning

confidence: 82%

Controversial issues in the management of older adults with early breast cancer

Mislang

Cheung

Hamaker

et al. 2017

Journal of Geriatric Oncology

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It is well recognized that the incidence of breast cancer increases significantly with age.Despite this, older people remain under-represented in many clinical trials and their management relies on extrapolation of data from younger patients. Providing an aggressive intervention can be challenging, particularly in less fit older patients where a conservative approach is commonly perceived to be more appropriate. The optimal management of this population is unknown and treatment decision should be personalized. This review article will discuss several controversial issues in managing older adults with early breast cancer in a multidisciplinary setting, including the role of surgical treatment of the axilla in clinically node negative disease, radiotherapy after breast conservation surgery in low-risk tumors, personalizing adjuvant systemic therapy, and geriatric assessments in breast cancer treatment decisions.

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Section: Triple Negative Ebcmentioning

confidence: 82%

Controversial issues in the management of older adults with early breast cancer

Mislang

Cheung

Hamaker

et al. 2017

Journal of Geriatric Oncology

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“…Récemment, il a été démontré qu'un outil prévisionnel fréquemment utilisé pour la prise de décision en matière de traitements systémiques, « Adjuvant! Online », fournissait des prévisions inexactes pour les patientes âgées, et qu'il fallait donc l'utiliser avec précaution pour ce groupe (de Glas et al, 2014). Le manque de précision de l'outil vient probablement de la proportion relativement faible de patientes plus âgées présentes dans les essais sur lesquels le programme est fondé, ainsi que les résultats liés aux maladies concomitantes entrés par les médecins (de Glas et al, 2014).…”

Section: Oncologie Médicale Traitements Systémiquesunclassified

Vers une approche multidisciplinaire optimale du traitement du cancer du sein chez les patientes plus âgées

Thavarajah¹,

Menjak²,

Trudeau³

et al. 2015

CONJ

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“…Standard oncology tools, such as Adjuvant! Online, can be suggestive, but should be used with caution, as their data estimates can be skewed in the elderly [ 11 ]. In addition, published predictive assessments are available, for example, for the risk of postsurgical complications: PACE/PREOP, Kristjansson [ 12 , 13 ].…”

Section: Decision Help Toolsmentioning

confidence: 99%

Geriatric Oncology

Extermann

Hussain²

2015

Tropical Hemato-Oncology

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Relevance to Tropical AreasAt fi rst glance, geriatric oncology might seem to be a problem limited to developed countries. Yet, as progresses have been made in sanitation, nutrition, and infectious disease prevention and treatment, life expectancy has markedly progressed in tropical countries. For example, the life expectancy at birth is now 65 years or more in 174 of 223 countries listed in the World Factbook, including countries such as India, Bangladesh, the Philippines, Indonesia, Brazil, or Egypt [ 1 ]. In fact in 2000, 59 % of the persons aged 65 and older lived in developing countries, and this proportion is projected to rise to 71 % by 2030 [ 2 ]. With this demographic trend comes an increased prevalence of chronic diseases, cancer being one of them. Therefore, medical teams training and planning for the management of cancer in the elderly will be a crucial component of good cancer care in tropical countries.

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Validity of Adjuvant! Online program in older patients with breast cancer: a population-based study

Cited by 82 publications

References 30 publications

Controversial issues in the management of older adults with early breast cancer

Controversial issues in the management of older adults with early breast cancer

Vers une approche multidisciplinaire optimale du traitement du cancer du sein chez les patientes plus âgées

Geriatric Oncology

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