Validity of simple clinical and biological parameters as screening tool for sickle cell anemia for referral to tertiary center in highly resource constraints

Abstract

These two biological markers may guide the clinician in the decision-making to initiate the management of the children as a sickle cell patient, pending confirmation of the disease by electrophoresis techniques.

Factitious disorder presenting as sickle cell disease: a case report

“…The challenge is that of suboptimal sensitivity, particularly in recently transfused individuals. 21 Select tests may aid diagnosis in emergent situations, but these have not been approved for this specific purpose and have limitations. These include rapid, qualitative solubility testing for the presence of sickling hemoglobin variants (e.g., HbS).…”