“…The continuous variables were the number of comorbid medical conditions, body mass index, depression determined using the Patient Health Questionnaire-9 (PHQ-9) [43], anxiety determined using the Hospital Anxiety and Depression Scale (HADS-A) [44], pain determined by the Pain Visual Analogue Scale (P-VAS) [45], sleep apnea determined using the STOP-Bang questionnaire [46], restless legs determined by adopted Restless Legs Questionnaire [47], and narcolepsy, as determined by the Swiss Narcolepsy Scale [48]. Binary variables were the severity of brain injury determined by the presence of loss of consciousness, retrograde or anterograde post-traumatic amnesia, the mechanism of injury, and the presence of previous head trauma; the presence of DSM-IV-TR disorders [13], including mood, anxiety, adjustment, substance-related, somatoform, sleep, and personality disorders; comorbid conditions (heart disease, arthritis, diabetes mellitus, thyroid dysfunction (hypo-or hyperthyroidism); and the symptom load impacting on sleep, such as snoring, observed pauses in breathing during sleep, head or neck pain, and bodily pain.…”