Background: The stress pregnant women feel causes adverse effects on healthy maternal-fetal attachment and accordingly, it is necessary to investigate the psychological factors that can alleviate it. Methods: The present study set a structural equation model to investigate whether mindfulness and self-compassion, which are valuable for mental health, promote maternal-fetal attachment by reducing the perceived stress. A total of 251 responses were collected through local hospitals, community health centers, and pregnancy-and child care-related online community web sites, and data were tested using a AMOS. Results: The results showed that the full mediation model in which each aspect of mindfulness and self-compassion promotes maternal-fetal attachment through perceived stress is most appropriate. Conclusions: The significance of the present study lies in looking into the relationships among these factors that have been researched individually so far by integrating them into a model. The limitations of the present study and directions for future research were discussed in the conclusion section.