Valorization and Physicochemical Characterization of Crude Plant Kernel Wax Obtained from Endocomia macrocoma (Miq.) W. J. de Wilde subsp. prainii (King) W. J. de Wilde

Barman, Rubi; Saikia, Jadumoni; Gayen, Firdaus Rahaman; Saha, Barna; Manna, Prasenjit; Haldar, Saikat; Pahari, Pallab; Saikia, Siddhartha Proteem; Banik, Dipanwita

doi:10.1007/s12649-022-01729-6

Cited by 3 publications

(1 citation statement)

References 45 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…After water, the most abundant ingredients in cosmetic formulations are emollients, among which wax esters are the predominant ones. According to the available literature, these esters can be obtained through different green methods: the most widely used is extraction from natural sources, [1][2][3][4][5][6] followed by the not common microbiological production, [7][8][9] and the emerging enzymatic synthesis using lipases and natural substrates. [10][11][12] Spermaceti is a wax composed of various high molecular weight esters that is often used as a lubricant and in the pharmaceutical and food industries.…”

Section: Introductionmentioning

confidence: 99%

Development of an industrial sustainable process for wax esters production: enzyme immobilization, process optimization, and plant simulation

Montiel

Serrano‐Arnaldos

Yagüe

et al. 2023

J of Chemical Tech & Biotech

View full text Add to dashboard Cite

BACKGROUND: As a result of the ban on whaling, there has been a shortage of spermaceti, a natural product with applications in cosmetics and pharmaceuticals. A green and sustainable process for the biocatalytic synthesis of a wax ester mixture analogue to natural spermaceti is presented in this paper.RESULTS: Immobilization of Candida antarctica lipase B by covalent binding to Purolite® Lifetech™ ECR8285 allowed for an immobilized derivative with 124.5 mg protein/g support (69.3% protein immobilization yield) that maintains 100% of its enzymatic activity after 12 months of cold storage and presents negligible loses of activity after 9 consecutive reaction cycles. The optimization of the synthesis process in a batch reactor resulted in conditions that, at 70 °C, 350 rpm, and 1.25% w/w of biocatalyst, achieved a conversion of 97% after 1 h of reaction. The simulation of a spermaceti production plant was carried out using the process simulation software aspenONE suite v10. The plant was designed for a continuous operation during 9 h per day, with a reactor of 20.25 L of working volume and a residence time of 1 h. The production of this plant would be 173.25 kg spermaceti/day, with a product purity of 99.55%. CONCLUSION:The main novelty of this work is the design of a spermaceti production plant, using the most sustainable methodologies and resulting in a product with exceptional characteristics and minimal waste generation. Moreover, a new lipase immobilized derivative is also described. The good values of sustainability indicators point to the viability of its industrial implementation.

show abstract