Valorization of Mexican Ricinus communis L. Leaves as a Source of Minerals and Antioxidant Compounds

Leal, José Fernando Vasco; Cuellar-Núñez, M. Liceth; Luzardo-Ocampo, Iván; Ventura-Ramos, Eusebio; Loarca-Piña, Guadalupe; Rodríguez‐García, Mario E.

doi:10.1007/s12649-020-01164-5

Cited by 6 publications

(10 citation statements)

References 58 publications

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“…Castor bean is a plant found in various regions of the world, mainly in tropical areas, and is widely used to produce castor oil. Castor bean leaves have been used as a medicinal plant due to the presence of phytochemicals, mainly phenolic compounds such as flavonoids (rutin, quercetin, and (+)-catechin), hydroxycinnamic acids (caffeic, chlorogenic, p -Coumaric, and sinapic acids), and hydroxybenzoic acids (gallic and ellagic acids) [ 15 ]. As a result of these compounds’ presence, the leaves and leaves extracts have been used for their anti-inflammatory [ 16 ] and anti-cancer effects [ 17 ].…”

Section: Introductionmentioning

confidence: 99%

Gold Nanoparticles Synthesized with Common Mullein (Verbascum thapsus) and Castor Bean (Ricinus communis) Ethanolic Extracts Displayed Antiproliferative Effects and Induced Caspase 3 Activity in Human HT29 and SW480 Cancer Cells

Soto¹,

Luzardo-Ocampo

López-Romero³

et al. 2022

Pharmaceutics

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Gold nanoparticles (AuNPs) are promising nanomaterials exhibiting anti-cancer effects. Green AuNPs synthesis using plant extracts can be used to achieve stable and beneficial nanoparticles due to their content of bioactive compounds. This research aimed to synthesize and evaluate the antiproliferative and caspase-3 activity induction of green AuNPs synthesized with common mullein (V. thapsus) flowers (AuNPsME) and castor bean (R. communis) leaves (AuNPsCE) ethanolic extracts in human HT29 and SW480 colorectal cancer cells. Their effect was compared with chemically synthesized AuNPs (AuNPsCS). The extracts mainly contained p-coumaric acid (71.88–79.93 µg/g), ferulic acid (19.07–310.71 µg/g), and rutin (8.14–13.31 µg/g). The obtained nanoparticles presented typical FT-IR bands confirming the inclusion of polyphenols from V. thapsus and R. communis and spherical/quasi-spherical morphologies with diameters in the 20.06–37.14 nm range. The nanoparticles (20–200 µg/mL) showed antiproliferative effects in both cell lines, with AuNPsCE being the most potent (IC50 HT29: 110.10 and IC50SW480: 64.57 µg/mL). The AuNPsCS showed the lowest intracellular reactive oxygen species (ROS) generation in SW480 cells. All treatments induced caspase 3/7 activity to a similar or greater extent than 30 mM H2O2-treated cells. Results indicated the suitability of V. thapsus and R. communis extracts to synthesize AuNPs, displaying a stronger antiproliferative effect than AuNPsCS.

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Section: Introductionmentioning

confidence: 99%

Gold Nanoparticles Synthesized with Common Mullein (Verbascum thapsus) and Castor Bean (Ricinus communis) Ethanolic Extracts Displayed Antiproliferative Effects and Induced Caspase 3 Activity in Human HT29 and SW480 Cancer Cells

Soto¹,

Luzardo-Ocampo

López-Romero³

et al. 2022

Pharmaceutics

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“…The fruit extract of Ricinus communis is a potent contender for the treatment of breast cancer 8 . Leaves of Ricinus communis contain tannins, flavonoids, cardiac glycosides, steroids, saponins, phlorotannis, and terpenoids that are considered as the essential bioactive constituents of any medicinal plants 19,26,29 . Ricinus communis leaves were screened for anthelmintic, anticonvulsant, and analgesic activity by many scientists 22,23,25 .…”

Section: Discussionmentioning

confidence: 99%

“…Flavanoids is beneficial against carcinogenesis as it inhibits oxidative damage. The untargeted metabolomic profiling and polyphenol showed the excess of phytoconstituents such as (+) catechin and ellagic acid, both of which are associated with antioxidant mechanism 18,19 .…”

Section: Antioxidantmentioning

confidence: 99%

Untitled

2021

IJPSR

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The medicinal plant Ricinus communis is one of the effective plants which offer a solution to several kinds of diseases. Owing to this, the present research aims to review the medicinal properties of one of such common herbal plants, Ricinus communis, its possible role as herbal medicine, and assessment for pharmacovigilance. Related research articles were collected from Google Scholar, Pub Med, Science direct, Scientific information Database, and Scopus. For the present study purpose, using the term Ricinus communis, the castor bean, and castor oil plant in the title of all articles published to 2021 were observed. Phytochemical constituents of R. communis like saponins, flavonoids, alkaloids, steroids, and glucosides. Leaves of the plant have shown the presence of major phenolic compounds. Whereas roots test has presented the Indole-3acetic. The findings reflect that the plant contains high medicinal benefits, which offer a solution for several kinds of diseases like cancer, diabetes, ulcer and anthelmintic, etc. Also, the plant is antiinflammatory property of the plant facilitates therapeutic use. Therefore, all parts of the medicinal plant R. communis are considered highly beneficial in the medicinal field.INTRODUCTION: Herbal plants have always been a viable source of medicine since prehistoric ages. Some of the isolated rural areas of developing and underdeveloped countries are still unable to get synthetic drugs easily. Traditional medicinal plants being easily available are used by many people to treat numerous illnesses. In India, 65-70% of the rural population rely on medicinal plants in the form of various indigenous ethnic systems like Ayurveda, Siddha, Unani, etc.

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“…Giving the high availability of wild R. communis in Mexico and other tropical countries and its insecticidal activity against species such as S. frugiperda and A. aegypti , it has been considered and used in insecticides [ 8 , 33 , 34 ].…”

Section: Discussionmentioning

confidence: 99%

Effect of Salicylic Acid in the Yield of Ricinine in Ricinus communis under Greenhouse Condition

Zavala-Gómez

Rodríguez-deLeón

Bah

et al. 2021

Plants

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Castor bean (Ricinus communis) seeds contain ricinine, an alkaloid with insecticidal and insectistatic activities. Elicitation with salicylic acid (SA) has proven to stress R. communis and might modify the ricinine concentration. The aim of this study was to evaluate the concentration of ricinine in the bagasse of seeds from R. communis elicited with exogenous SA under greenhouse conditions. Plants were grown and divided into five groups, which were sprayed with SA and drench with 50 mL 60 days after sowing with concentrations of SA (0, 100, 300, 600 and 900 µM). Clusters were mixed and separated according to the treatment, and dried. The seeds were ground, the oil was extracted by Soxhlet with hexane, and then the bagasse was extracted with methanol. Ricinine was determined by HPLC. Elicitation did not change the plant height or diameter; the control group had 9.17 µg mL−1 of ricinine; and the concentrations followed a hormesis curve with the peak at 300 µM of SA that had a ricinine concentration of 18.25 µg mL−1. Elicitation with SA might be a cost-effective technique to increase ricinine from R. communis bagasse.

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Valorization of Mexican Ricinus communis L. Leaves as a Source of Minerals and Antioxidant Compounds

Cited by 6 publications

References 58 publications

Gold Nanoparticles Synthesized with Common Mullein (Verbascum thapsus) and Castor Bean (Ricinus communis) Ethanolic Extracts Displayed Antiproliferative Effects and Induced Caspase 3 Activity in Human HT29 and SW480 Cancer Cells

Gold Nanoparticles Synthesized with Common Mullein (Verbascum thapsus) and Castor Bean (Ricinus communis) Ethanolic Extracts Displayed Antiproliferative Effects and Induced Caspase 3 Activity in Human HT29 and SW480 Cancer Cells

Untitled

Effect of Salicylic Acid in the Yield of Ricinine in Ricinus communis under Greenhouse Condition

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