Valorization of Phaeodactylum tricornutum for integrated preparation of diadinoxanthin and fucoxanthin

Zhuang, GengJie; Ye, Yuemei; Zhao, Jianqing; Zhou, Chengxu; Zhu, Junwang; Li, Yanrong; Zhang, Jinrong; Yan, Xiaojun

doi:10.1016/j.biortech.2023.129412

Cited by 5 publications

(1 citation statement)

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“…These microorganisms are highly efficient in fixing CO 2 and producing biomass by capturing sunlight. In addition, their biomass production capacity is four times greater than other vegetable sources (Zhuang et al, 2023). The need for nutrients such as nitrogen, phosphorus, carbon or potassium during cultivation also makes it possible to use the culture stage of these microorganisms in wastewater bioremediation treatments.…”

Section: Introductionmentioning

confidence: 99%

Phaeodactylum tricornutum as a stable platform for pilot scale production and investigation of the viability of spirulina fucoxanthin as a commercial lipolysis active novel compound

Delgado-Ramallo,

Álvarez-Gil,

Casado-Bañares

et al. 2024

Front. Mar. Sci.

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The nutraceutical market has experienced a significant growth over the last years, due to changing consumer preferences towards products of natural and organic origin. One of the main areas of interest in this field is microalgae-derived carotenoids, whose antioxidant activity protects against oxidative damage in human cells. The diatom Phaeodactylum tricornutum has been widely studied due to its high fucoxanthin content (antioxidant carotenoid). However, pilot and industrial scale experiments to realize continuous and stable production of P. tricornutum and extracted fucoxanthin are limited. For this reason, this research focuses on the study of the fucoxanthin production, going through culture, harvesting, scaling procedure and encapsulation stage. Finally, the optimal culture conditions for a fucoxanthin production of 2.5 mg/day/L were verified. Furthermore, the antioxidant capacity showed a decrease during storage, but still presented a capacity of 18 months, with improved performance when encapsulated with spirulina. The study carried out on encapsulated fucoxanthin-spirulina shows an inhibitory effect on lipogenesis at all concentrations tested in the 3T3-L1 cell line and a lipolytic efficacy at concentrations of 0.2 mg/mL and 0.1 mg/mL in the 3T3-L1 cell line.

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Section: Introductionmentioning

confidence: 99%