Valorization of renewable resources to functional oligosaccharides: Recent trends and future prospective

Narisetty, Vivek; Parhi, Priyanka; Binoop, Mohan; Hazeena, Sulfath Hakkim; Kumar, Avanish; Gullón, Beatriz; Srivastava, Anita; Nair, Lakshmi M.; Alphy, Maria Paul; Sindhu, Raveendran; Kumar, Vinod; Castro, Eulógio; Awasthi, Mukesh Kumar

doi:10.1016/j.biortech.2021.126590

Cited by 25 publications

(11 citation statements)

References 105 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It can be found in different raw materials such as bamboo shoots, fruits, vegetables, wheat bran and straw, corn cobs, sugarcane residues, and rice straw [10]. These compounds consist of xylose units linked by β- (1,4) bonds (Figure 1) and may have several functional groups such as arabinosyl residues, acetyl groups, and uronic or phenolic acids [8], which mainly depends on the raw material of origin. The type of biomass used can also lead to different degrees of polymerization (DP), between two and seven xylose units, pattern of substitutions of the main chain and types of bonds [4,8].…”

Section: Xylooligosaccharides (Xos) Characteristics and Bibliometric ...mentioning

confidence: 99%

Xylooligosaccharides: A Bibliometric Analysis and Current Advances of This Bioactive Food Chemical as a Potential Product in Biorefineries’ Portfolios

Manicardi

Silva

Longati

et al. 2023

Foods

View full text Add to dashboard Cite

Xylooligosaccharides (XOS) are nondigestible compounds of great interest for food and pharmaceutical industries due to their beneficial prebiotic, antibacterial, antioxidant, and antitumor properties. The market size of XOS is increasing significantly, which makes its production from lignocellulosic biomass an interesting approach to the valorization of the hemicellulose fraction of biomass, which is currently underused. This review comprehensively discusses XOS production from lignocellulosic biomass, aiming at its application in integrated biorefineries. A bibliometric analysis is carried out highlighting the main players in the field. XOS production yields after different biomass pretreatment methods are critically discussed using Microsoft PowerBI® (2.92.706.0) software, which involves screening important trends for decision-making. Enzymatic hydrolysis and the major XOS purification strategies are also explored. Finally, the integration of XOS production into biorefineries, with special attention to economic and environmental aspects, is assessed, providing important information for the implementation of biorefineries containing XOS in their portfolio.

show abstract

Section: Xylooligosaccharides (Xos) Characteristics and Bibliometric ...mentioning

confidence: 99%

Xylooligosaccharides: A Bibliometric Analysis and Current Advances of This Bioactive Food Chemical as a Potential Product in Biorefineries’ Portfolios

Manicardi

Silva

Longati

et al. 2023

Foods

View full text Add to dashboard Cite

show abstract

“…Hydrolysate obtained through the OAAH-3 treatment was subjected to centrifugation at 6000 rpm for 10 min. AC (3,6,9,12, and 15% (w/v)) was added to the supernatant and stirred at 200 rpm for 1 h at room temperature. After centrifugation, the supernatant was discarded and the pellet was washed with MQ water twice to remove unbound impurities.…”

Section: Activated Charcoal-mediated Purification (Acmp) Of Xosmentioning

confidence: 99%

“…The bioactive-rich agro-industry waste utilization for the production of value-added products not only reduces the production cost but also minimizes the pollution load from the environment . This lignocellulosic waste can be valorized by the production of the oligosaccharide and ultimately contribute to cyclic bioeconomics …”

Section: Introductionmentioning

confidence: 99%

“…2 This lignocellulosic waste can be valorized by the production of the oligosaccharide and ultimately contribute to cyclic bioeconomics. 3 Xylooligosaccharide (XOS) is a nondigestible functional product derived through chemical, physical, enzymatic, and thermal degradation of xylan, obtained from hemicellulose-rich biomass. 4,5 Hemicellulose is a polysaccharide made of xylose, galactose, arabinose, mannose, and glucuronic acid.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Green Downstream Processing Method for Xylooligosaccharide Purification and Assessment of Its Prebiotic Properties

Sonkar,

Gade,

Mudliar

et al. 2023

ACS Omega

View full text Add to dashboard Cite

Xylooligosaccharides (XOS) obtained from lignocellulosic biomass after autohydrolysis primarily consist of ligninderived impurities and autogenerated inhibitors like furfural, hydroxymethylfurfural, and acetic acid. In this study, graphene oxide-mediated purification (GOMP), a novel and environmentally friendly downstream processing method, was developed for the purification of XOS from hydrolysate obtained after ozone-assisted autohydrolysis of wheat bran. GOMP resulted in appreciable recovery of total XOS from the hydrolysate (73.87 ± 4.25%, DP2− 6) with near complete removal of autogenerated inhibitors (furfural 85.42%, HMF 87.38%, and acetic acid 84.0%). Recovery of XOS by GOMP was higher than the conventional membrane purification technique (44.07 ± 0.92%) and activated charcoal treatment (72.76 ± 0.84%) along with comparatively higher removal of inhibitor compounds. GOMP results in the selective adsorption of inhibitors on the graphene oxide matrix from the XOS-rich hydrolysate, resulting in its purification and concentration. The prebiotic function of the obtained XOS fractions (DP2−4.48%, DP3−39.69%, DP4−36.13%, DP5−8.38%, and DP6−13.10%) was evaluated, indicating the growth stimulation of tested probiotic cultures and differential utilization of XOS oligomers DP3 and DP4 and complete consumption of DP2, DP5, and DP6 along with short-chain fatty acids as a major fermentation product. These findings suggest that GOMP, which employs a common substance (i.e., graphene oxide) used in water treatment, exhibits potential as an efficient and economically viable single-step methodology for XOS purification.

show abstract

“…Biomass can be biologically converted into bioethanol and other economically important products such as lactate, butanol, bioplastic etc. [5][6][7][8][9][10].…”

Section: Introductionmentioning

confidence: 99%

Adaptation on xylose improves glucose–xylose co-utilization and ethanol production in a carbon catabolite repression (CCR) compromised ethanologenic strain

2022

View full text Add to dashboard Cite

Background Sugar hydrolysates from lignocellulosic biomass are majorly composed of glucose and xylose that can be fermented to biofuels. Bacteria, despite having the natural ability to consume xylose are unable to consume it in presence of glucose due to a carbon catabolite repression (CCR) mechanism. This leads to overall reduced productivity as well as incomplete xylose utilization due to ethanol build-up from glucose utilization. In our effort to develop a strain for simultaneous fermentation of glucose and xylose into ethanol, we deleted ptsG in ethanologenic E. coli SSK42 to make it deficient in CCR and performed adaptive laboratory evolution to achieve accelerated growth rate, sugar consumption and ethanol production. Finally, we performed proteomics study to identify changes that might have been responsible for the observed improved phenotype of the evolved strain. Results The parental strain of SSK42, i.e., wild-type E. coli B, did not co-utilize glucose and xylose as expected. After deleting the ptsG gene encoding the EIIBCGlc subunit of PTS system, glucose consumption is severely affected in wild-type E. coli B. However, the ethanologenic, SSK42 strain, which was evolved in our earlier study on both glucose and xylose, didn’t show such a drastic effect of EIIBCGlc deletion, instead consumed glucose first, followed by xylose without delay for switching from one sugar to another. To improve growth on xylose and co-utilization capabilities, the ptsG deleted SSK42 was evolved on xylose. The strain evolved for 78 generations, strain SCD78, displayed significant co-utilization of glucose and xylose sugars. At the bioreactor level, the strain SCD78 produced 3-times the ethanol titer of the parent strain with significant glucose–xylose co-utilization. The rate of glucose and xylose consumption also increased 3.4-fold and 3-fold, respectively. Proteome data indicates significant upregulation of TCA cycle proteins, respiration-related proteins, and some transporters, which may have a role in increasing the total sugar consumption and co-utilization of sugars. Conclusion Through adaptive evolution, we have obtained a strain that has a significant glucose–xylose co-utilization phenotype with 3-fold higher total sugar consumption rate and ethanol production rate compared to the unevolved strain. This study also points out that adaptation on xylose is enough to impart glucose–xylose co-utilization property in CCR compromised ethanologenic strain SSK42.

show abstract

Valorization of renewable resources to functional oligosaccharides: Recent trends and future prospective

Cited by 25 publications

References 105 publications

Xylooligosaccharides: A Bibliometric Analysis and Current Advances of This Bioactive Food Chemical as a Potential Product in Biorefineries’ Portfolios

Xylooligosaccharides: A Bibliometric Analysis and Current Advances of This Bioactive Food Chemical as a Potential Product in Biorefineries’ Portfolios

Green Downstream Processing Method for Xylooligosaccharide Purification and Assessment of Its Prebiotic Properties

Adaptation on xylose improves glucose–xylose co-utilization and ethanol production in a carbon catabolite repression (CCR) compromised ethanologenic strain

Contact Info

Product

Resources

About