Valorization of the Phosphate Fertilizers Catalytic Activity in 1-(Benzothiazolylamino) Methyl-2-Naphthol Derivatives Synthesis

Abstract

The present work focused on developing a new protocol of the 1-(benzothiazolylamino) methyl-2-naphthol derivatives synthesis by condensation of three compounds, i.e. aromatic 2-naphthol, 2-aminobenzothiazole and aldehyde. Furthermore, this reaction was carried out in the presence of three heterogeneous phosphate catalysts: monoammonium phosphates (MAP), diammonium phosphate (DAP), and trisuperphosphate (TSP). Moreover, this method offered many advantages, such as: very high yields, shorter reaction times, and the catalysts, can be easily recovered and reused without any loss of their catalytic activities. Copyright ©2019 BCREC Group. All rights reserved

Comparative study between the Titanium Phosphate TiP2O7 and the Phosphate Fertilizers in the catalysis of the Quinazolin-4(3H)-one derivatives synthesis

“…As a continuation of the previous works developed by our researchers [27][28][29][30][31][32][33][34][35][36][37][38][39] , which consist on the valorization of Moroccan phosphates in the field of organic synthesis, and the development of green and sustainable chemistry, this paper reports the first and an easy preparation method for TiP2O7 from the modifications of phosphate fertilizers MAP, DAP and TSP by titanium tetrachloride (TiCl4). The characterization of TiP2O7 was realized using spectroscopic and microscopic technics such as XRD, IR, SEM, and EDX.…”

Eco-friendly Synthesis of Quinoxaline Derivatives Using Mineral Fertilizers as Heterogeneous Catalysts

“…attracted considerable interest since their basic skeleton involved as a core structure of several drug molecules such as quinacillin (15), brimonidine (16), varenicline (17), clofazimine (18), echinomycin (19)(20) and actinomycin (21). Some other quinoxalinecontaining compounds have shown many biological properties (22), such as antimicrobial (23), antidiabetic (24), anti-inflammatory (25), antioxidant (25), anticancer (26), antileishmanial and antitrypanosomal (27) activities.…”

“…Motivated by the desire to introduce a new generation of phosphate-based heterogeneous catalysts, our laboratory was particularly interested in the catalytic performance evaluation of some phosphate fertilizers for Knoevenagel condensation and 1-(benzothiazolylamino)-methyl-1-2-naphthol derivatives (14)(15).…”

Fe3O4@MCM‐41@ZrCl2: A novel magnetic mesoporous nanocomposite catalyst including zirconium nanoparticles for the synthesis of 1‐(benzothiazolylamino)phenylmethyl‐2‐naphthols

“…Betti's base, a structure called 1-(α-aminoalkyl)-2-naphthols with two active amino and hydroxyl groups, plays a major role in synthetic chemistry due to the possibility of C-C bond formation under mild laboratory conditions. [58] These benefits have navigated numerous efforts to synthesize 1-(benzothiazolyl amino)phenylmethyl-2-naphthols employing various catalysts such as sodium dodecyl sulfate (SDS), [59] NaHSO 4 .H 2 O, [60] heteropolyacid (HPA), [61] maltose, [62] 3-methyl-1-(4-sulfonic acid) propylimidazolium hydrogen sulfate [(CH 2 ) 3 SO 3 HMIM] [HSO 4 ], [63] fumaric acid, [64] oxalic acid, [58] ɤ-aminobutyric acid (GABA), [65] phosphate fertilizers, [66] and NH 3 (CH 2 ) 5 NH 3 BiCl 5 . [67] Although all reports have their own credits, some defects such as toxicity and expensiveness of the catalyst, environmental pollution, challenging synthesis, inaccessible reactions, long-term reaction times, and undesirable yields are still notable.…”