In this paper we address the topic of capital budgeting in highly dynamic and innovative industries, featuring major uncertainties with respect to the future development and acceptance of technologies and end-user products in the market. Focusing on the nanomaterials industry, a model has been developed using empirical data and integrating features of life cycle costing (LCC) and parametric simulation (Monte Carlo). A recursive solution of LCC allows an end-product benchmark costing for the materials, which currently lack commodity market pricing, while the simulation provides a valuation utility for the technology-specific flexibility to switch production. The underlying research offers a broad scope of applications in potentially high-value-added environments.