Valuation of EQ-5D-5L Health States in Poland: the First EQ-VT-Based Study in Central and Eastern Europe

Abstract

ObjectiveCost-utility analyses are becoming increasingly important in Central and Eastern Europe. We aimed to develop a Polish utility tariff for EQ-5D-5L health states.MethodsFace-to-face, computer-assisted interviews were collected in a representative sample. Each respondent followed a standardised protocol to collect ten composite time trade-off and seven discrete choice experiment observations. In the Bayesian approach, several model specifications were compared based on model fit, the usability of the final value set and how they reflect the elicitation procedure (e.g. censoring). A hybrid approach (using composite time trade-off and discrete choice experiment data) was employed in the final set, which was compared with the existing ones: EQ-5D-3L and EQ-5D-5L cross-walk.ResultsData from 1252 respondents (11,480 composite time trade-off valuations and 8764 discrete choice experiment pairs) were collected over the period June to October 2016. The final model accounted for random parameters, error scaling with fat tails, censoring at − 1, unwillingness to trade in time trade-off by the religious people and Cauchy distribution in discrete choice experiments. Pain/discomfort impacts the utility most: the disutility equals 0.575 when at level 5. In the value set, 4.4% of EQ-5D-5L states are worse than dead. The new value set has a comparable range (minimum of − 0.590 compared to − 0.523) and the same ordering of the first three dimensions (pain/discomfort, mobility, self-care) as the EQ-5D-3L value set and the EQ-5D-5L cross-walk value set. Moreover, it is more sensitive to a moderate decline in health.ConclusionsThe new value set supports consistency with past decisions in cost-utility studies, while offering a better assessment of even moderate improvements in health. It could represent an option for Central and Eastern Europe countries lacking their own value sets.Electronic supplementary materialThe online version of this article (10.1007/s40273-019-00811-7) contains supplementary material, which is available to authorized users.

Population norms of health-related quality of life in Moscow, Russia: the EQ-5D-5L-based survey

“…The Russian version of EQ-5D-5L has been successfully validated in a group of 163 patients with spondylarthritis [34]. Recent years have witnessed attempts to carry out EQ-5D-3L valuation [35,36], which should soon result in the final publication of a country-specific Russian value set [11]. The availability of validated tools should facilitate international comparisons, which up to now have been based mainly on general economic and social indicators [37][38][39].…”

EQ-5D-5L Bulgarian population norms

“…As there is no available Bulgarian value set yet, we used the Polish EQ-5D-5L directly measured value set to estimate EQ-5D-5L index values. At the moment of the study, it was the only EQ-5D-5L value set coming from Central and Eastern Europe [35]. EQ-5D index values illustrate societal preferences for different health states and range from -0.590 to 1.0, where negative values correspond to bad health conditions (states worse than death), and 1.0 corresponds to perfect health.…”

Valuing health-related quality of life among the Indian population: a protocol for the Development of an EQ-5D Value set for India using an Extended design (DEVINE) Study

“…This approach has been used in several national EQ-5D-5L valuation studies. [25][26][27][28][29][30][31][32][33] The hybrid model will combine the likelihood functions of a linear model for the c-TTO data and a logit model for the DCE data. As the coefficients will be estimated from a conditional logit and expressed on a latent arbitrary utility scale, we will use a rescaled parameter θ, which will assume that the c-TTO model coefficients are proportional to DCE model coefficients.…”