Value and limitations of the Continuous Glucose Monitoring System in the management of type 1 diabetes

Improving the Estimation of Meal-Time Insulin Dose Based On the Glycaemic Load of a Meal in Children with Type 1 Diabetes on Insulin Pump Therapy: A Randomized Study

“…CGMS is a valuable method to assess glucose trends, but it does not accurately reflect glucose levels in the blood. On the other hand, it allows the identification of overlooked hyper-or hypoglycaemia [19]. After various types of food consumption, glycaemia remains above the baseline for a longer period, and the CGMS is a convenient method to determine the glucose response.…”

Changes in the Glycemic Profiles of Women With Type 1 and Type 2 Diabetes During Pregnancy

“…We recognize that like all monitoring systems, CGMS is not without limitations, in particular with regard to the quality of readings during rapid blood glucose changes and in the lower hypoglycemic ranges (35). However, from this vast quantity of continuously monitored data, we have gained unprecedented insights into the magnitude, frequency, and duration of blood glucose fluctuations in women with type 1 and type 2 diabetes during pregnancy.…”

Continuous Glucose Monitoring in Gastroparesis

“…Inclusion criteria for normal subjects included the following: (1) ages 18-75 years; (2) absence of diabetes or gastroparesis; (3) absence of gastroparetic symptoms: defined as a GCSI score of B9; and (4) absence of other major gastrointestinal symptoms (heartburn, nausea, vomiting, constipation). Exclusion criteria for all subjects included the following: (1) pregnancy; (2) prior abdominal surgery except appendectomy, cholecystectomy, hysterectomy, hernia repair; (3) another active disorder which could explain symptoms; (4) unable to provide informed consent; (5) uncontrolled diabetes (HgbA1c [10) and or glucose determinations [400 mg/dl; (6) taking regular narcotic medications; and (7) receiving enteral nutrition or total parenteral nutrition (TPN).…”

“…However, periodic fingerstick glucose measurements represent only a few minutes of the day and may not indicate the direction or trend for glucose levels. Continuous glucose monitoring (CGM) uses a subcutaneous catheter that measures interstitial glucose which reflects systemic blood glucose [10]. CGM allows more careful assessment of glucose regulation [11,12] by being able to assess fluctuations in blood sugar readings (both hypoglycemia and hyperglycemia) that cannot be measured by the intermittent blood sugar determinations.…”