Value of 18F-FDG PET/CT imaging in the staging, restaging, monitoring of response to therapy and surveillance of uterine leiomyosarcomas

Belissant, Ophélie; Champion, Laurence; Thevenet, H. Slimani; Weinmann, Pierre; Alberini, Jean-Louis

doi:10.1097/mnm.0000000000000848

Cited by 6 publications

(3 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Among the radiologic imaging approaches, magnetic resonance imaging (MRI) represents the best approach to imaging of uterine sarcomas, owing to its improved ability to define local spread of disease [15], while computed tomography scan (CT scan) is preferred for staging, assessment of distant metastases and follow-up [16]. Moreover, also the 18-fluoro-D-glucose positron emission tomography ( 18 FDG PET) has been attempted as a diagnostic tool and could eventually be useful; however, current data are limited [17,18].…”

Section: Resultsmentioning

confidence: 99%

Italian consensus conference on management of uterine sarcomas on behalf of S.I.G.O. (Societa’ italiana di Ginecologia E Ostetricia)

Ferrandina

Aristei²,

Biondetti

et al. 2020

European Journal of Cancer

View full text Add to dashboard Cite

Section: Resultsmentioning

confidence: 99%

Italian consensus conference on management of uterine sarcomas on behalf of S.I.G.O. (Societa’ italiana di Ginecologia E Ostetricia)

Ferrandina

Aristei²,

Biondetti

et al. 2020

European Journal of Cancer

View full text Add to dashboard Cite

“…Roberg et al reported cases of different types of sarcomas, where 10/91 PET negative results of distal metastasis turned out to be incorrect, while CT scans provided reliable data [4]. In a study by Bélissant et al, in 2 described cases of patients with leiomyosarcoma, metastases in the lung and peritoneum were not detected by PET [11]. However, the use of CT alone is not advisable either.…”

Section: Discussionmentioning

confidence: 99%

Liver metastasis or a pseudocyst? A rare presentation of leiomyosarcoma’s metastasis in the liver

Bednarek¹,

Sołek²,

Szymczyk³

et al. 2022

View full text Add to dashboard Cite

Gastrointestinal neoplasms most commonly metastasize to the liver, where they are typically found as solid and hypervascular lesions. Here, we describe a case of a 44-year-old man with a leiomyosarcoma of the rectum, who at the time of diagnosis presented with a small (5 mm in diameter) cyst-like lesion in the liver. Positron emission tomography demonstrated no increased metabolism in the area of the cyst, suggesting a benign character of the lesion. However, after 3 years, CT scans revealed enlargement of the cyst, and local surgical excision was performed. The results of histopathological examination of the resected material were consistent with metastatic leiomyosarcoma. Subsequently, the patient developed lung metastases and died within 2 years. Our case describes a very rare presentation of leiomyosarcoma’s metastasis that led to an ill-fated misdiagnosis and dismal disease outcome.

show abstract

“…To date, the predominant literature on the subject of preoperative imaging of uterine tumors pertains to MRI, both conventional and functional [5 ▪▪ ,6–9,10 ▪ ,11]. Although the utility of PET in local staging and surveillance for recurrence in leiomyosarcoma has been reported [12,13], its use for differentiating leiomyosarcoma from leiomyoma is less well established, with only a few studies having been reported on the topic [14–18]. Imaging findings for other rarer tumors, such as adenosarcoma, are primarily based on case reports and lack consensus, rendering presurgical diagnosis challenging [19,20].…”

Section: Introductionmentioning

confidence: 99%

New imaging modalities to distinguish rare uterine mesenchymal cancers from benign uterine lesions

Andrieu

Woo

Kim

et al. 2021

Current Opinion in Oncology

View full text Add to dashboard Cite

Purpose of reviewUterine sarcomas are rare and are often challenging to differentiate on imaging from benign mimics, such as leiomyoma. As functional MRI techniques have improved and new adjuncts, such as machine learning and texture analysis, are now being investigated, it is helpful to be aware of the current literature on imaging features that may sometimes allow for preoperative distinction.Recent findings MRI, with both conventional and functional imaging, is the modality of choice for evaluating uterine mesenchymal tumors, especially in differentiating uterine leiomyosarcoma from leiomyoma through validated diagnostic algorithms. MRI is sometimes helpful in differentiating high-grade stromal sarcoma from low-grade stromal sarcoma or differentiating endometrial stromal sarcoma from endometrial carcinoma. However, imaging remains nonspecific for evaluating rarer neoplasms, such as uterine tumor resembling ovarian sex cord tumor or perivascular epithelioid cell tumor, primarily because of the small number and power of relevant studies.

show abstract

Value of 18F-FDG PET/CT imaging in the staging, restaging, monitoring of response to therapy and surveillance of uterine leiomyosarcomas

Cited by 6 publications

References 26 publications

Italian consensus conference on management of uterine sarcomas on behalf of S.I.G.O. (Societa’ italiana di Ginecologia E Ostetricia)

Italian consensus conference on management of uterine sarcomas on behalf of S.I.G.O. (Societa’ italiana di Ginecologia E Ostetricia)

Liver metastasis or a pseudocyst? A rare presentation of leiomyosarcoma’s metastasis in the liver

New imaging modalities to distinguish rare uterine mesenchymal cancers from benign uterine lesions

Contact Info

Product

Resources

About