477The early diagnosis of patients suspected of having renovascular hypertension is important because of the risk of progression to renal insufficiency due to the nephropathic ischemia caused by lesions limiting the renal artery flow.The diagnosis of arterial hypertension resulting from renal artery stenosis may be established with the following different complementary examinations: determination of selective renin in the renal vein; functional study with radioisotopes; excretory urography; determination of the peripheral renin stimulated with captopril; magnetic angioresonance; angiography; and, more recently, vascular color Doppler ultrasound.Arteriography is the most precise method for diagnosing renal artery stenosis, but it has some limitations, such as allergic reaction and the risk of nephrotoxicity due to the contrast medium, in addition to complications inherent to the procedure and its high cost. Another important factor is that arteriography is an anatomic study, and, therefore, does not provide hemodynamic information about the renal lesions.This study aimed at assessing the accuracy of vascular color Doppler ultrasound as compared with that of arteriography in identifying hemodynamically significant renal artery stenoses.
MethodsWe carried out a prospective double-blind study at the Noninvasive Vascular Laboratory of the Hospital de Caridade of the Santa Casa de Misericórdia de Curitiba/PUCPR, to assess the accuracy of vascular color Doppler ultrasound in the diagnosis of stenotic or obstructive lesions in the renal arteries as compared with that of arteriography, which is considered the gold standard.One hundred and thirty-seven renal arteries from 69 adult patients (30 men and 39 women) suspected of having renovascular arterial hypertension, with no distinction of complexion or biotype, and a mean age of 54 years were studied. One of the patients had undergone nephrectomy prior to the study.The following patients with arterial hypertension of recent onset were included in the study: young individuals with no familial history of hypertension; individuals > 55 years with arterial hypertension of recent onset or abrupt lack of control; hypertensive individuals refractory to treatment; hypertensive individuals with an abdominal murmur; and individuals with predominantly diastolic arterial hypertension (> 120 mmHg). Patients with the following characteristics were excluded from the study: previous diagnosis of renal artery lesion; history of allergy to iodinated contrast me-
ObjectiveTo assess the accuracy of vascular color Doppler ultrasound as compared with digital subtraction arteriography for identifying hemodynamically significant renal artery stenoses.
MethodsOne hundred and thirty-seven renal arteries from 69 adult patients suspected of having renovascular arterial hypertension were prospectively studied with ultrasound. The results obtained were compared in a double-blind manner with those obtained on digital subtraction arteriography, and the following parameters were calculated according to ...