Value of Drumsticks and Other Nuclear Appendices in the Determination of Sex. Discriminatory Analysis Based on Findings in 804 Normal Subjects

Procópio-Valle, J; Chagas, W.A.; Manceau, J. N.

doi:10.1210/jcem-21-8-965

Cited by 5 publications

(1 citation statement)

References 13 publications

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“…Other studies have shown drumsticks in up to 17% of neutrophils in the peripheral smear of a healthy women. [10][11][12] Form B was seen with slightly higher frequency among females whereas Form C was observed with increased frequency among males with average of 7.4 compared to females' average of 2.3. The difference of A-C gives a positive value in females and negative value in males.…”

Section: Discussionmentioning

confidence: 99%

Reliability of neutrophilic nuclear appendages in morphological sex differentiation

Verma¹,

Adinarayan²

2017

Int J Med Sci Public Health

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Background:The inactive X-chromosome in neutrophils appears in one of the three forms. They are drumsticks, racquet forms, and sessile nodules. Objective: A correlative study based on the presence of "drumstick and other nuclear appendages" in polymorphonuclear neutrophils to determine the morphological sex. Materials and Methods: Sixty-eight randomly selected blood smears (34 males and 34 females) were stained with Leishman's stain. One hundred well-stained neutrophils were double-blindly studied in the tail-end of the smears and classified into four groups based on Kosenow's formula as drumstick (Form A), sessile nodule (Form B), and other pedunculated nuclear projections such as tag and hooks (Form C). Results: Significant correlation of neutrophilic nuclear appendage of Form A (P = 0.00001) and Form C (P = 0.00016) was obtained for females and males, respectively. Difference of A-C gives a positive value in females and a negative value in males. Conclusion: Neutrophilic nuclear appendages which include true drumsticks, sessile nodules, and racket structures form a useful tool for morphological sex differentiation. ABSTRACT Access this article onlineWebsite: http://www.ijmsph.com Quick Response code

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Section: Discussionmentioning

confidence: 99%