Value of exercise testing for screening asymptomatic men for latent coronary artery disease

Froelicher, Victor F.; Thompson, Amanda; Longo, Michael; Triebwasser, John H.; Lancaster, M. C.

doi:10.1016/0033-0620(76)90022-0

Cited by 207 publications

(36 citation statements)

References 48 publications

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“…Participants in the Seattle Heart Watch study 81 and the Lipid Research Clinics Program, 82 United States Air Force personnel, 18 Norwegian office workers 19 and Indiana State Police employees 83 are among the "normal" asymptomatic populations who have been subjected to exercise testing and followed prospectively to investigate the prognostic significance of electrocardiographic evidence of ischemia. Epstein et al 84 combined results of the studies of Bruce 81 and Erikksen 85 to estimate that of 10 000 asymptomatic individuals, 500 (5%) had an abnormal exercise test; of these individuals, 50% had angiographic coronary disease.…”

Section: Asymptomatic Populationsmentioning

confidence: 99%

Silent Myocardial Ischemia

2003

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Section: Asymptomatic Populationsmentioning

confidence: 99%

Silent Myocardial Ischemia

2003

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“…The frequency of positive exercise electrocardiograms in asymptomatic middle-aged diabetic subjects has varied from 14 to 23% (14-16) compared with a prevalence of 6-12% (17)(18)(19) in asymptomatic nondiabetic subjects of similar age. Although exercise electrocardiogram is a more sensitive method than resting electrocardiogram, its reliability in totally asymptomatic subjects has been questioned because according to Bayes's theorem, the probability of false positive findings is high (20). The lack of specificity is also a problem in thallium imaging.…”

Section: Silent Coronary Artery Disease and Diabetesthementioning

confidence: 99%

Association Between Silent Coronary Artery Disease, Diabetes, and Autonomic Neuropathy: Fact or Fallacy?

Airaksinen

Koistinen

1992

Diabetes Care

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“…Otherwise, we could not detect any regional abnormalities in the contraction pattern of the left ventricle during any of the tests. 4 A blinded restudy of the baseline angiograms were found in the latter three men; specifically, none had developed symptoms or resting ECG signs indicative of CHD. Echocardiographic examination revealed no signs of valvular disease in any of the men reported in this study, and in particular no mitral valve prolapse was apparent.…”

Section: Resultsmentioning

confidence: 96%

“…[1][2][3][4][5][6] In addition to the ST segment response, important information is obtained through the study of parameters such as maximal heart rate obtained, level According to the survey findings, the patients were subdivided into groups as shown in figure 1. Of 115 with suspected latent CHD, 109 gave their informed consent for coronary angiography.…”

Section: Exercise Electrocardiographic (Ecg)mentioning

confidence: 99%

False suspicion of coronary heart disease: a 7 year follow-up study of 36 apparently healthy middle-aged men.

Erikssen¹,

Dale²,

Rootwelt³

et al. 1983

Circulation

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Latent coronary heart disease was suspected in 115 of 2014 apparently healthy middleaged men after a baseline cardiovascular survey. One hundred five of these men underwent angiography and 36 were found to have normal coronary arteries (group 1). A 7 year follow-up survey revealed that: (1) three had died of sudden cardiac death, (2) four had received a diagnosis of cardiomyopathy, (3) one had developed aortic dilatation/aortic regurgitation since the baseline survey, (4) they all had a significantly more rapid decline in their physical performance and maximal heart rate levels from the time of the baseline survey to follow-up than did randomly selected normal controls (group 2), and (5) thallium study results were normal in both groups (27 and 26 patients), but technetium ventriculography revealed a subnormal increase in ejection fraction during exercise (< 5% units) in 14 of 27 group 1 subjects and in 4 of 26 group 2 subjects. Thus, incipient heart disease may be present in subjects in whom coronary angiographic examination has removed a previous suspicion of coronary heart disease.Circulation 68, No. 3, 490-497, 1983. EXERCISE ELECTROCARDIOGRAPHIC (ECG) testing is valuable in the evaluation of patients with chest pain and as a screening procedure in apparently healthy subjects. For the purpose of this study, performed 6 to 9 years after the one described above, the "angionegatives" were assigned to group I, and the men participating as control subjects (group 2) were selected as follows. Each time one of the men from group I was examined, the next man to be examined was designated a normal control subject, provided he belonged to the normal CIRCULATION

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Value of exercise testing for screening asymptomatic men for latent coronary artery disease

Cited by 207 publications

References 48 publications

Silent Myocardial Ischemia

Silent Myocardial Ischemia

Association Between Silent Coronary Artery Disease, Diabetes, and Autonomic Neuropathy: Fact or Fallacy?

False suspicion of coronary heart disease: a 7 year follow-up study of 36 apparently healthy middle-aged men.

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