Value of gallium-67 scanning in differentiation of malignant tumors from benign tumors or inflammatory disease in the oral and maxillofacial region

Li, Ningyi; Zhu, Weihong; Zuo, Shi; Jia, Muyun; Sun, Jian

doi:10.1016/s1079-2104(03)00349-4

Cited by 9 publications

(17 citation statements)

References 9 publications

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“…9 Another radioactive isotope, gallium-67 ( 67 Ga), has been widely utilized for the imaging study of various malignant tumors. 10 Accumulation of 67 Ga can be detected in inflammatory lesions that facilitate help on diagnosis of different major salivary gland diseases, as Sjo¨gren's Syndrome. 10 However, few studies regarding major salivary glands damage using scintigraphy were published.…”

Section: Introductionmentioning

confidence: 99%

Major salivary gland damage in allogeneic hematopoietic progenitor cell transplantation assessed by scintigraphic methods

Coracin

Corrêa

Camargo

et al. 2006

Bone Marrow Transplant

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Salivary gland dysfunction is a common sequela of hematopoietic progenitor cell transplantation (HPCT). The investigation of major salivary gland dysfunction with sodium pertechnetate scintigraphy is a non-invasive method that provides images of the parotid and submandibular glands. In this prospective trial, 20 HPCT patients were submitted to scintigraphic study with 99m Tcpertechenate and 67 Ga in order to evaluate the major salivary glands early involvement following HPCT. Major salivary glands were evaluated prior to HCPT as well as at Days þ 30, þ 60 and þ 100 post transplant. Major salivary glands uptake and clearance of 99m Tc-pertechenate results did not demonstrate any functional differences between pre-versus post transplant periods. Results of the 67 Ga scan revealed inflammatory infiltration following HPCT, primarily in submandibular glands, suggest a persistent involvement of major salivary glands up to Day þ 100 after HPCT. Bone Marrow Transplantation (2006) 37, 955-959.

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Section: Introductionmentioning

confidence: 99%

Major salivary gland damage in allogeneic hematopoietic progenitor cell transplantation assessed by scintigraphic methods

Coracin

Corrêa

Camargo

et al. 2006

Bone Marrow Transplant

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“…Some reports on the usefulness of this imaging modality have been published [1][2][3][4][5][6][7]. The diagnostic ability of planar imaging is increased by its combination with SPECT, but few published reports have discussed this increase in detail [10][11][12][13].…”

Section: Discussionmentioning

confidence: 99%

“…Gallium (Ga) scintigraphy is often used in cases of malignant head and neck diseases to detect primary, metastatic, or recurrent lesions [1][2][3] and to evaluate the responses of lesions to treatment (surgery, radiotherapy, chemotherapy, and so on) [4][5][6][7]. In patients suspected of having head and neck lesions, Ga-single-photon emission computed tomography (SPECT) is often performed in addition to planar imaging for the purpose of establishing a diagnosis [8,9].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of diagnostic abilities of Ga-SPECT for head and neck lesions

Kotani

Kawabe²,

Higashiyama³

et al. 2008

Ann Nucl Med

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This study revealed the marked superiority of SPECT images over planar images in terms of the ability to detect primary tumors and tumor metastasis to cervical lymph nodes. Furthermore, the primary T1 tumor detection rate of SPECT images was higher than that of CT images. On the basis of these results, the concomitant use of SPECT is highly recommended when Ga scintigraphy is performed to check for malignant head/neck tumors.

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“…Thus, gallium is absorbed in the inflammation zones. Table 1 summarizes some important usages of this radioisotope in inflammation [7][8][9][10][11][12]. Idiopathic pulmonary fibrosis Lung [7] Differentiation of malignant/benign/inflammatory Oral/maxillofacial region [8] Pulmonary Wegener's granulomatosis Chest/nasal region [9] Chronic bronchial asthma Respiratory tract [10,11] Sarcoidosis Pulmonary activity [12] …”

Section: -Gallium-67 Scintigraphymentioning

confidence: 99%

Application of Radioisotopes in Inflammation

Jalilian¹,

Bineshmarvasti²,

Sardari

2006

CMC

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Since the discovery of artificially produced radioisotopes in the 1930's, an estimated 10-12 million nuclear medicine diagnostic and therapeutic procedures are currently performed each year only in the United States. Gamma emission imaging has been successfully applied to almost every organ of the body (brain, bone, heart, kidney, lung, neuroreceptors) as well as sites of inflammation, atherosclerosis, and thrombosis. FDG-PET has been used in some of the inflammatory diseases as well. On the other hand, both alpha and beta-emitting isotopes have been evaluated for brachytherapy of rheumatoid diseases, each with different radiobiological effectiveness. The current status of radionuclides for imaging, therapy and research studies of inflammatory processes is reviewed here and a look into the future directions is described at the conclusion.

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Value of gallium-67 scanning in differentiation of malignant tumors from benign tumors or inflammatory disease in the oral and maxillofacial region

Cited by 9 publications

References 9 publications

Major salivary gland damage in allogeneic hematopoietic progenitor cell transplantation assessed by scintigraphic methods

Major salivary gland damage in allogeneic hematopoietic progenitor cell transplantation assessed by scintigraphic methods

Evaluation of diagnostic abilities of Ga-SPECT for head and neck lesions

Application of Radioisotopes in Inflammation

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