Value of MRI in Characterizing Adnexal Masses

Karnik, Alpana; Tembey, Raina Anil; Mani, Sanjeev

doi:10.1007/s13224-015-0730-9

Cited by 8 publications

(12 citation statements)

References 6 publications

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“…Several imaging modalities are available for making a specific diagnosis among patients with adnexal mass ( 50 ). However, these modalities cannot replace histopathology or biopsy as the gold standard for diagnosis.…”

Section: Discussionmentioning

confidence: 99%

Diagnostic accuracy of transvaginal ultrasound examination for assigning a specific diagnosis to adnexal masses: A meta‑analysis

Zhang

Meng²,

Dou³

et al. 2020

Exp Ther Med

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Transvaginal ultrasound (TVUS) is a standard imaging modality for differentiating patients with benign or malignant suspected adnexal mass. To date, numerous studies have assessed the diagnostic accuracy of TVUS in various settings but with variable results. Therefore, the purpose of the present study was to perform a meta-analysis to evaluate the diagnostic accuracy of TVUS for the differentiation of adnexal masses. An electronic search in the Medline, Scopus, Cochrane and Embase databases from inception till November 2019 was carried out. Meta-analysis was performed to obtain pooled sensitivity and specificity of TVUS to distinguish malignant from benign adnexal masses. The quality assessment of diagnostic accuracy studies-2 tool was used to assess the quality of trials. A total of 41 studies with 18,391 patients were included. The pooled sensitivity and specificity of TVUS was 92% (95% CI: 90-94%) and 89% (95% CI: 85-92%), respectively. The area under the receiver operating characteristic curve was 0.96 (95% CI: 0.84-1.00). There was considerable heterogeneity with a statistically significant chi-square test (P<0.001) and I 2 of 99%. Meta-regression results indicated that index test standards, patient selection bias and study design were potential sources of heterogeneity (P<0.05). The funnel plot was symmetrical and low publication bias was confirmed by an insignificant Deek's test (P=0.90). The present systematic review and meta-analysis indicated that TVUS is useful in differentiating between benign and malignant tumours among patients with suspected adnexal mass with high sensitivity and specificity.

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Section: Discussionmentioning

confidence: 99%

Diagnostic accuracy of transvaginal ultrasound examination for assigning a specific diagnosis to adnexal masses: A meta‑analysis

Zhang

Meng²,

Dou³

et al. 2020

Exp Ther Med

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“…Imaging plays an important role in the early diagnosis of ovarian cancers, thus improving the surgical results and decreasing morbidity and mortality rates (13). The MRI is a leader in increasing the characterization of adnexal masses and thus increasing the specificity particularly for indeterminate lesions by ultrasound and for extremely large masses (14). The present study revealed validity results of MRI in the diagnosis of malignant adnexal tumors as sensitivity (90.9%), specificity (75%), +ve predictive value (90.9%), -ve predictive value (75%) and accuracy (86.6%).…”

Section: Discussionmentioning

confidence: 99%

The accuracy of pelvic magnetic resonance imaging in the diagnosis of ovarian malignancy in Iraqi patients in comparison with histopathology

Mohson¹

2019

J. Fac. Med Baghdad

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Background: Ovarian malignancy is considered to score the highest fatality among women due to lack of significant symptoms. Early diagnosis and treatment lead to good prognosis. Magnetic resonance imaging (MRI) plays a major role in the diagnosis by detecting the lesions and assessing their appearance and consistency. Objective: To determine the accuracy of MRI in the diagnosis of ovarian malignancy and comparing this to histopathology as a gold standard test. Patients and methods: A follow up study was conducted in the MRI unit of the Radiology Department in Baghdad Teaching Hospital / Baghdad Medical City Complex during the period from 1 st of February to 31 st of December, 2017 on a group of thirty women with clinically suspected adnexal mass(es). All patients were examined with MRI including the diffusion-weighted imaging. Surgical specimens were taken for histopathology assessment. Results: A total of 30 women with adnexal mass were included in this study, with a mean age of 46.8±14.9 years. The MRI T1W image of the cystic part was dark in (60%), while the T2W image of the cystic part was bright (80%), T2W of the solid part was bright in (53.3%), T2W fat saturation of the solid part was bright in the majority (73.3%). T1W fat suppression contrast-enhanced of the solid part was avid in 66.7% of women with an adnexal mass; DWI of the solid part was bright in (76.7%). The mean apparent diffusion coefficient (ADC) value by MRI for women with adnexal mass was 0.9±0.3x103 mm2/sec. Histopathology mainly revealed mucinous cystadenocarcinoma in (10%) and low-grade serous adenocarcinoma in (10%).Validity of the results of MRI regarding malignant adnexal mass were sensitivity (90.9%), specificity (75%), +ve predictive value (90.9%),-ve predictive value (75%) and accuracy (86.6%). The appropriate cutoff value for apparent diffusion coefficient in differentiation between malignant and benign adnexal mass was 0.97 with 100% sensitivity and 90.9% specificity. Conclusions: MRI and diffusion-weighted imaging is a valid and reliable technique in the diagnosis and characterization of ovarian malignancy.

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“…2 Levels below 35 U/mL were considered normal. 3 Large (more than 12/12 cm) solid, fixed or irregular adnexal masses suspicious of malignancy were treated by laparotomy. Trans-vaginal ultrasound scanning was used as primary imaging (Matsushita H et al).…”

Section: Methodsmentioning

confidence: 99%

“…The predictive value is about 96% in detection of the benign masses. 3 The procedure, being non-invasive, is widely acceptable for establishing the diagnosis. Magnetic resonance imaging (MRI) increases the specificity of imaging evaluation for adnexal masses, especially when they are indeterminate on ultrasound.…”

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confidence: 99%

Laparoscopic management of adnexal masses: a hospital-based study

Bhattacharjee

Sharma

2018

Int J Reprod Contracept Obstet Gynecol

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Background: Laparoscopy is a widely used procedure in gynecological cases both for diagnostic and operative purposes. Laparoscopic surgery has been associated with early recovery, shorter duration of hospital stay and significant patient satisfaction. The present study is conducted to evaluate the effectiveness and safety of laparoscopy in the management of adnexal masses. Primary aim of this study is to find out the indications, intraoperative findings and the different interventions contemplated to deal with the adnexal masses.Methods: The study period was of 7 months, from July 2017 to January 2018, in the Dept of Obstetrics and Gynecology, MGM Medical College and M.Y. Hospitals Indore, MP. During this period, 63 patients underwent laparoscopy for various adnexal masses. Cases were critically analyzed and results were presented.Results: Most of the patients were from the age-group 25-30 yrs. Most common indication was ovarian tumor of varied pathology. Most common surgical procedure performed was ovarian cystectomy. The most common histopathological finding was functional ovarian cyst. Only 3.1% of cases needed conversion to laparotomy for the completion of the procedure. Complication rate was minimal.Conclusions: Laparoscopy due to its lesser adverse effects, less postoperative pain, shorter stay in hospital, small erre-admission rates, better panoramic vision is considered more beneficial than laparotomy. Careful patient selection and availability of a experts should be taken into account. The current study is an over view of our experience in favor of laparoscopy in treatment of a large population of women with benign adnexal masses.

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Value of MRI in Characterizing Adnexal Masses

Cited by 8 publications

References 6 publications

Diagnostic accuracy of transvaginal ultrasound examination for assigning a specific diagnosis to adnexal masses: A meta‑analysis

Diagnostic accuracy of transvaginal ultrasound examination for assigning a specific diagnosis to adnexal masses: A meta‑analysis

The accuracy of pelvic magnetic resonance imaging in the diagnosis of ovarian malignancy in Iraqi patients in comparison with histopathology

Laparoscopic management of adnexal masses: a hospital-based study

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