Value of radionuclide oesophageal transit in studies of functional dysphagia

Abstract

Radionuclide oesophageal transit time was evaluated in 70 individuals, divided into three groups: normal individuals, patients with non-organic dysphagia and patients with primary oesophageal motility disorders treated with per-endoscopic forced pneumatic dilatation. In all of them the oesophageal transit time of a bolus of water with 18.5 MBq (500 microCi) of 99Tmc sulphur colloid was assessed, as was the percentage of residual activity of the bolus in the oesophagus. There was a significant difference in these parameters between the control group and the group with non-organic dysphagia, the diagnostic capacity of this test being 93% sensitivity, 100% specificity, 100% positive predictive value and 90% negative predictive value, which suggests its inclusion in diagnostic protocols of dysphagias. In patients with primary oesophageal motility disorders, a significant decrease in values of residual activity has been observed after treatment with per-endoscopic forced pneumatic dilatation.

Recommendation for supportive care in patients receiving concurrent chemotherapy and radiotherapy for lung cancer

“…Disorders of esophageal motility may also lead to dysphagia. 20 Severe, long-lasting acute esophagitis may evolve to late damage such as strictures and perforation. Serious acute esophagitis may not only result in a decreased intake of food, but also of liquids, which may lead to dehydration.…”