Value of sonographically guided fine needle aspiration biopsy in evaluating the liver with sonographic abnormalities

Sautereau, Denis; Vire, O.; Cazes, P.Y.; Cazals, J.B.; Catanzano, G; Claude, R.; Pillegand, B

doi:10.1016/0016-5085(87)90432-x

Cited by 24 publications

(6 citation statements)

References 22 publications

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“…We generally perform US examinations, at 1-to 3-month intervals, in cases when a malignancy cannot be ruled out. Ultrasonically guided fine-needle biopsy is a pertinent tool to confirm the diagnosis of focal liver disease (17,18). Although use of such a procedure will lead to a definite diagnosis, physicians should keep in mind that it is sometimes extremely difficult to distinguish between well-differentiated HCC and normal tissue when only a fragment of tissue is obtained by needle biopsy.…”

Section: Discussionmentioning

confidence: 99%

Angiographically Undetected Small Hepatocellular Carcinoma: Clinicopathological Characteristics, Follow–Up and Treatment

et al. 1989

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We studied 36 cases (38 nodules) of small hepatocellular carcinoma with special attention directed to detectability using angiography and histology. Among the 38 nodules, 31 nodules (81.6%) were evident. The remaining seven (18.4%) were not evident angiographically but were detected using ultrasonography and/or computed tomography, prior to angiography. An elevated level of serum alpha-fetoprotein also suggested a diagnosis of hepatocellular carcinoma. When comparisons were made between angiographically detected and undetected nodules, there was no statistically significant difference in parameters, including sex of the patient, tumor size, location of the tumor, positive rate for hepatitis B surface antigen, history of liver disease and values of alpha-fetoprotein. The small hepatocellular carcinomas not detected angiographically and evidenced only histologically had the following characteristics: (i) no fibrous capsule surrounding the nodules; (ii) well-differentiated tumors; (iii) replacing growth pattern of cancer cells, and (iv) remains of portal tracts within the tumor. The replacing growth pattern and the presence of portal tracts may correlate with the low detectability in angiography. When a definite diagnosis of angiographically undetectable tumors cannot be made using close surveillance with ultrasonography or alpha-fetoprotein and/or needle biopsy under ultrasonic guide, surgical intervention should be considered, particularly for patients at high risk for hepatocellular carcinoma.

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Section: Discussionmentioning

confidence: 99%

Angiographically Undetected Small Hepatocellular Carcinoma: Clinicopathological Characteristics, Follow–Up and Treatment

et al. 1989

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“…space-occupying lesions has been widely validated so that nowadays the use of fine and largebore needles to achieve a morphologic diagnosis (cytologic and histologic) has been accepted as a routine procedure, often capable of shortening diagnostic workup of patients. [5][6][7] Similarly, sonographically guided therapeutic procedures have often changed the treatment approach by offering an effective alternative to established surgical treatment modalities in a variety of pathologic conditions: (1) primary and secondary liver neoplasms may be destroyed in situ by means of either chemical (ethanol or acetic acid) or physical (radio frequency-, laser-, or microwave-induced hyperthermia) agents [8][9][10][11][12][13][14] ;…”

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confidence: 99%

Complications After Interventional Sonography of Focal Liver Lesions

Giorgio

Tarantino

Stefano

et al. 2003

Journal of Ultrasound in Medicine

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“…Similar problems have been encountered in other studies. 29,30 In this study, FNA of gall bladder masses was performed in 11 patients. Of them, 7 had definite features of adenocarcinoma.…”

Section: Discussionmentioning

confidence: 99%

Utility of image guided fine needle aspiration cytology in the evaluation of intra-abdominal and retroperitoneal lesions at a tertiary health care center in Kashmir valley

Parveen

Lone

Rashid³

et al. 2020

Int J Adv Med

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Background: FNAC has become an established investigation in the diagnosis of accessible and palpable lesions. Most of the intra-abdominal masses are non-palpable and even if they are palpable, the idea of their size and shape and the extent of the lesion is not possible. Therefore, various imaging modalities like ultra-sonography, computed tomography and fluoroscopy are used as a guide for fine needle aspiration nowadays. Objectives of this study were to assess the utility of image guided fine needle aspiration cytology in the diagnosis of non-palpable intra-abdominal lesions. To study the cytomorphological features of these lesions. To evaluate the sensitivity, specificity and diagnostic accuracy of image guided fine needle aspiration cytology of these lesions.Methods: A prospective study of percutaneous aspiration biopsy of intra-abdominal masses, to evaluate its utility was undertaken in the department of pathology, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Kashmir. FNA was performed in 183 patients.Results: Adequate cell sample was obtained in majority of the cases (83.6%). Majority of the abdominal masses were arising from the liver (65%). Location of abdominal masses also included those arising from pancreas (12.02%), kidneys (7.65%), lymph nodes (7.65%), Gall bladder (6%) omental deposits (1.09%) and adrenal gland (0.54%). Majority of US guided FNA was done in liver masses. Overall sensitivity, specificity and diagnostic accuracy of image guided FNAC of intra-abdominal and retroperitoneal masses of the study was 100%, 100% and 93.54%, respectively.Conclusions: There is lack of awareness regarding dog bite and its management among the rural population.

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Value of sonographically guided fine needle aspiration biopsy in evaluating the liver with sonographic abnormalities

Cited by 24 publications

References 22 publications

Angiographically Undetected Small Hepatocellular Carcinoma: Clinicopathological Characteristics, Follow–Up and Treatment

Angiographically Undetected Small Hepatocellular Carcinoma: Clinicopathological Characteristics, Follow–Up and Treatment

Complications After Interventional Sonography of Focal Liver Lesions

Utility of image guided fine needle aspiration cytology in the evaluation of intra-abdominal and retroperitoneal lesions at a tertiary health care center in Kashmir valley

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