2013
DOI: 10.1016/j.amjsurg.2013.03.007
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Value of the pretreatment albumin to globulin ratio in predicting long-term mortality in breast cancer patients

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Cited by 117 publications
(107 citation statements)
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“…These observations are consistent with previously provided evidence (53). By way of example, reported that the serum level of albumin can be implemented as an independent predictor for survival of breast cancer patients (54).…”
supporting
confidence: 92%
“…These observations are consistent with previously provided evidence (53). By way of example, reported that the serum level of albumin can be implemented as an independent predictor for survival of breast cancer patients (54).…”
supporting
confidence: 92%
“…We observed that low preoperative AGR (<1.36) could still identify patients who had a poorer prognosis, even if their serum albumin levels were normal (≥35 g/L; OR=1.7; 95% CI, 1.2-2.6; p=0.008). Secondly, AGR is calculated in the form of two values, which can avoid the influences of hemodilution or hemoconcentration (14). However, we cannot also evade the disadvantages of AGR.…”
Section: Discussionmentioning
confidence: 99%
“…To the best of our knowledge, several previous studies have demonstrated the correlation between the preoperative AGR and long-term survival of cancers (9)(10)(11)(12)(13)(14), but GC has not been discussed. The purpose of this study was to find the cutoff value of AGR and to evaluate whether preoperative AGR has a prognostic value in patients with resectable GC.…”
mentioning
confidence: 98%
“…The ALB to GLB ratio (AGR = ALB/(total serum protein À ALB) is the ratio of serum ALB to non-ALB proteins (i.e., GLB and other protein particles). A decreased ALB level and increased GLB level reflect chronic inflammation [16][17][18]. As systemic inflammation causes an increase in the levels of various proinflammatory cytokines, which subsequently promote tumor progression because of changes in the cancer microenvironment [19,20], a decreased AGR is thought to correlate with tumor progression.…”
Section: Introductionmentioning
confidence: 99%