Value of three-section contrast-enhanced transrectal ultrasonography in the detection of prostate cancer

Qi, Tingyue; Sun, Hongyan; Li, Nianfen; Feng, Hao; Ding, Yun; Wang, Xiaoxiang

doi:10.1002/jcu.22458

Cited by 3 publications

(2 citation statements)

References 19 publications

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“…Perfusion can also be evaluated using contrastenhanced ultrasound (CEUS). Whilst good results have been demonstrated for CEUS of lesions 0.5 mL or larger, (sensitivity of 58-69% and specificity of 93-95%), 26 a study by Qi et al 41 found that three section CEUS was able to detect 92.3% of patients with cancer, whereas standard TRUS identified only 70.7%. The cohort for both studies, however, all had clinically significant cancer (Gleeson 7) and had subsequent prostatectomy.…”

Section: Perfusion Characteristicsmentioning

confidence: 99%

The role of diagnostic ultrasound imaging for patients with known prostate cancer within an active surveillance pathway: A systematic review

et al. 2021

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Background The use of multiparametric magnetic resonance imaging (mpMRI) within active surveillance of prostate cancer programmes is identified by the UK National Institute for Health and Care Excellence (NICE guideline NG 131 2019) as having a role for monitoring disease. The widespread demands on mpMRI capacity may limit its use in surveillance. It is therefore timely to review the options that modern ultrasound imaging present to this cohort of patients in the monitoring of prostate cancer. Methods Between April and September 2020, 10 databases were searched to recruit studies for the review. Three reviewers evaluated the publications for inclusion. Characteristics including the inclusion criteria for the study cohort, how disease was determined, identification of disease progression, and the modality and mode of imaging used were reviewed. Given the paucity of full text articles, a meta-analysis was not possible. A narrative review was undertaken. Results In total, 12 studies, utilising the range of ultrasound parameters of B-mode, micro-ultrasound, colour Doppler, contrast ultrasound and elastography were included. The review demonstrated that micro-ultrasound offers promise as an imaging tool comparable with mpMRI. However, this is an emerging technology with limited availability. Analysis of the data further demonstrated that by combining the diagnostic features provided by multiple modes reviewed, ultrasound has a role in the diagnostic imaging of patients on active surveillance. Conclusion Providing a multiparametric approach is utilised, stable ultrasound findings may allow for increased intervals between biopsy for men on surveillance. The advent of micro-US offers promise as an imaging modality within an active surveillance pathway but requires further verification.

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Section: Perfusion Characteristicsmentioning

confidence: 99%

The role of diagnostic ultrasound imaging for patients with known prostate cancer within an active surveillance pathway: A systematic review

et al. 2021

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“…The higher rate of low grade PCa detected allowed the selection of the patients for active surveillance [29].…”

Section: New Ultrasound Techniquesmentioning

confidence: 99%

Prostate ultrasound: back in business!

et al. 2017

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The use of grey scale prostate ultrasound decreased after the implementation of magnetic resonance imaging (MRI) for the diagnosis and evaluation of prostate cancer. The new developments, such as multiparametric ultrasound and MRI-ultrasound fusion technology, renewed the interest for this imaging method in the assessment of prostate cancer. The purpose of this paper was to review the current role of prostate ultrasound in the setting of these new applications. A thorough reevaluation of the selection criteria of the patients is required to assess which patients would benefit from multiparametric ultrasound, who wouldbenefit from multiparametric MRI or the combination of both to assist prostate biopsy in order to ensure the balance between overdiagnosis and underdiagnosis of prostate cancer.

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Diagnostic performance of reduced field-of-view diffusion-weighted imaging-targeted biopsy in suspected prostate cancer patients: A comparison with systematic biopsy

Sun

et al. 2022

Digital Medicine

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Purpose: To clarify the diagnostic performance of reduced field-of-view (rFOV) diffusion-weighted imaging (DWI) and compare prostate cancer (PCa) detection rates of rFOV DWI-targeted biopsy (rFOV DWI-TB) with systemic biopsy (SB). Materials and Methods: Ninety-eight consecutive patients with suspected PCa (mean prostate-specific antigen [PSA]: 17.85 ng/mL, range, 4-28 ng/mL) were prospectively enrolled in this study. All rFOV DWI data were carried out using PI-RADS V 2.0 assessment category. All patients underwent a 10-core SB and a further 2-4 cores of rFOV DWI-TB. The performance of rFOV DWI was analyzed, and the cancer detection rates between two methods were compared. Results: The sensitivity, specificity, positive predictive value, and negative predictive value for detecting PCa with rFOV DWI were 85.11%, 92.16%, 90.91%, and 87.04%, respectively. Area under curve for rFOV DWI was 0.886. In the digital rectal examination (DRE) normal and PSA ≥ 10 ng/mL subgroups, the PCa detection rates were statistically greater for rFOV DWI-TB than for SB (both P < 0.05). The mean Gleason score of cancers detected by rFOV DWI-TB was significantly higher than that detected by SB (P < 0.05). In addition, the detection rate for rFOV DWI-TB cores was significantly better than for SB cores (P < 0.001). Conclusion: RFOV DWI allowed for good diagnostic performance in patients suspected of PCa. It may be useful for clinically significant PCa detecting.

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Value of three-section contrast-enhanced transrectal ultrasonography in the detection of prostate cancer

Abstract: Our study demonstrated a significant benefit of three-section CETRUS relative to conventional CETRUS, and this technique may find more PCa patients eligible for active surveillance. © 2016 Wiley Periodicals, Inc. J Clin Ultrasound 45:304-309, 2017.

Cited by 3 publications

References 19 publications

The role of diagnostic ultrasound imaging for patients with known prostate cancer within an active surveillance pathway: A systematic review

The role of diagnostic ultrasound imaging for patients with known prostate cancer within an active surveillance pathway: A systematic review

Prostate ultrasound: back in business!

Diagnostic performance of reduced field-of-view diffusion-weighted imaging-targeted biopsy in suspected prostate cancer patients: A comparison with systematic biopsy

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