Value of viscosity, viscoelasticity and attenuation measurement using shear wave ultrasound elastography

Sporea, Ioan; Bâldea, Victor; Lupușoru, Raluca; Lazăr, Alin; Fofiu, Renata; Popescu, Alina; Şirli, Roxana

doi:10.1016/j.ultrasmedbio.2019.07.393

Cited by 2 publications

(2 citation statements)

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“…Another quantitative parameter of liver damage that was evaluated was shear‐wave dispersion (SWD), which is indicative of liver viscosity, and has shown potential to be an indicator of inflammatory processes within the liver. 41 , 42 Ultrasound frequency influences shear wave speed and the measurement of the level of dependency of shear waves to frequency is called dispersion. This in turn is correlated to viscosity.…”

Section: Methodsmentioning

confidence: 99%

Post‐COVID‐19 Liver Injury: Comprehensive Imaging With Multiparametric Ultrasound

Radziņa

Putriņš

Mičena

et al. 2021

J of Ultrasound Medicine

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Objectives This study aimed to define patterns of liver injury after severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection using multiparametric ultrasound (mpUS) in a variable patient population with differing severities of COVID‐19. Methods Ninety patients were enrolled into the study: 56 had SARS‐CoV‐2 3–9 months prior to enrolment; 34 served as a clinically healthy control group. All patients underwent an mpUS evaluation of the liver (elastography, dispersion and attenuation imaging). Seventy‐six patients had abdominal magnetic resonance (MR) and noncontrast enhanced thoracic computed tomography (CT) scans performed at the same day. All patients were screened for biochemical markers of liver injury. Results Liver elasticity, viscosity, and steatosis values were significantly altered in patients after COVID‐19, with particularly higher fibrosis scores compared to the control group ( P < .001). Increased biochemical markers of liver injury correlated with changes in mpUS ( P < .05), but not with findings on CT or MR findings. Seventeen of 34 hospitalized patients had a moderate or severe course of the disease course with more pronounced changes in mpUS. Increased body mass index was found to influence liver injury and correlated with more severe forms of COVID‐19 ( P < .001). Conclusions COVID‐19 can cause liver injury observable using mpUS. More severe forms of COVID‐19 and patient obesity are related to increased values of liver damage observed. In comparison to MRI and CT, mpUS appears to be more sensitive to involvement of liver parenchyma. Further research is warranted to establish this promising method for evaluating post‐COVID‐19 liver involvement in the aftermath of the pandemic.

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Section: Methodsmentioning

confidence: 99%

Post‐COVID‐19 Liver Injury: Comprehensive Imaging With Multiparametric Ultrasound

Radziņa

Putriņš

Mičena

et al. 2021

J of Ultrasound Medicine

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“…Values of this parameter are expressed in dB/cm/MHz and it also has a parameter of the quality of acquisition, that must be higher than R 2 >0.90( Figure 6a). In a preliminary study in which ATI was compared with CAP (FibroScan, EchoSens), in a cohort of 113 consecutive subjects [25], a strong positive correlation was found between the attenuation coefficients of steatosis obtained by the 2 methods, r = 0.81, p < 0.001. Using CAP as reference, the AUROCs of ATI for ≥S1, ≥S2 and ≥S3 were excellent (0.89, 0.88, respectively 0.95, p < 0.001) and the proposed cut-off values for were: S1 = 0.64 dB/cm/mHz, S2 = 0.79 dB/cm/mHz and S3 = 0.86 dB/cm/mHz.…”

Section: Attenuation Image (Ati)mentioning

confidence: 96%

Quantification of Liver Steatosis

Sporea¹,

Şirli²,

Popescu³

2020

Ultrasound Elastography

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The prevalence of non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) is increasing in the modern world. Fatty infiltration of the liver can be assessed by standard ultrasound, by controlled attenuation parameter (CAP) using the FibroScan device or, more recently, by ultrasound systems that evaluate the attenuation in the liver. Standard ultrasound (US) for steatosis evaluation was used for a long time as a semi-quantitative method for steatosis assessment in the liver. A "bright liver" with "posterior attenuation" is the typical US sign of liver steatosis. Considering the attenuation severity, steatosis is subjectively graded as mild, moderate or severe. Using the kidney/liver ratio, a more accurate evaluation can be made. Controlled attenuation parameter (CAP) was developed by EchoSens, France, and implemented into the FibroScan device. CAP manages an objective assessment of steatosis severity with rather good accuracy. More recently, ultrasound companies such as Hitachi, General Electric and Canon, implemented in their system algorithms which allow an objective assessment of liver steatosis, using the attenuation of the ultrasound beams.

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Value of viscosity, viscoelasticity and attenuation measurement using shear wave ultrasound elastography

Cited by 2 publications

References 0 publications

Post‐COVID‐19 Liver Injury: Comprehensive Imaging With Multiparametric Ultrasound

Post‐COVID‐19 Liver Injury: Comprehensive Imaging With Multiparametric Ultrasound

Quantification of Liver Steatosis

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