Value of wireless capsule endoscopy in patients with indeterminate colitis (inflammatory bowel disease type unclassified)

Capsule endoscopy in inflammatory bowel disease type unclassified and indeterminate colitis serologically negative

“…8 In the setting of IBDU/IC, several studies on the benefit of CE for its evaluation have been published. [6][7][8] These small pilot studies found that the use of CE led to a change in the diagnosis of 29%-40% of patients. 6 A recent multicenter study 7 looked at 30 seronegative IBDU/IC patients with a mean duration of disease of 6 years (range 1-18).…”

“…[6][7][8] These small pilot studies found that the use of CE led to a change in the diagnosis of 29%-40% of patients. 6 A recent multicenter study 7 looked at 30 seronegative IBDU/IC patients with a mean duration of disease of 6 years (range 1-18). An initial CE was positive in 5 patients, with a mean duration of disease of 4 years (range 1-9), who were later diagnosed with CD.…”

“…6 Several studies have examined the potential role of CE in the setting of IBDU/IC, suggesting that CE is useful in the work-up of these patients by ruling out small-bowel lesions suggestive of CD. [6][7][8] Despite these new developments, a long-term follow-up is often the only way to determine the correct diagnosis. The aim of our study is to evaluate the clinical impact of CE on long-standing IBDU and IC patients with negative serology.…”

Role of capsule endoscopy in inflammatory bowel disease

“…Another series included 30 patients with IBDU, in whom CD (defined as 3 or more SB ulcers) was identified in 5. Interestingly, in 6/25 VCE-negative patients CD was diagnosed on a subsequent ileocolonoscopy with biopsies [42] . In a series of pediatric patients, 5/7 patients initially diagnosed as UC or IBDU were reclassified as having CD as a result of VCE findings [43] (Table 4).…”

“…In 9/23 patients with UC, the Lewis score of inflammation was consistent with mild to moderate small bowel inflammation (between 135 and 790). The clinical and pathological significance of these lesions is unclear (repeated biopsies were performed in only 2 patients, but these results are of great interest and em- [42] IBDU 30 > 3 ulcerations-diagnostic of CD, 1-2 ulcerations-suggestive of CD…”