“…In 2020, the Centers for Disease Control and Prevention of the United States reported more cases of carbapenem-resistant Acinetobacter (increased by 78%), antifungal-resistant Candida auris (increased by 60%), and carbapenem-resistant Enterobacterales (increased by 35%) than in 2019, possibly due to more and sicker patients during the pandemic who required more frequent and longer use of catheters and ventilators, personal protective equipment and laboratory supply challenges, fewer healthcare staff, and longer lengths of stay. 3 Outbreaks of multidrug-resistant organisms, including carbapenem-resistant Acinetobacter baumannii, 4,5 C auris 6 and Enterobacterales, 7 as well as vancomycin-resistant Enterococcus, 8,9 have been reported in healthcare facilities. In a systematic review that identified 17 outbreaks during the COVID-19 pandemic caused mainly by carbapenem-resistant Acinetobacter baumannii and C auris, inadequate personal protective equipment or hand hygiene adherence, personal protective equipment shortage, and high antibiotic use were the most commonly reported modifiable factors contributing to the outbreaks.…”