Vanishing Bronchus Syndrome

Kesavan, Ramesh; Haddad, Tarik; Lunn, William; Jayaraman, Gnananandh; Ganesh, Sivagini; Loebe, M.; Lan, Charlie; Shetty, Rajesh; Murray, Carmen; Seethamraju, Harish

doi:10.1378/chest.132.4_meetingabstracts.595b

Cited by 7 publications

(6 citation statements)

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“…Complete bronchial atresia ultimately developed in six of the seven patients with an associated high mortality reported with five patients dying of respiratory failure; the mean survival after VBIS diagnosis being 25.3 months (range 1-76) and overall survival of 31.1 ± 25.9 months (21). The following year, Kesavan et al (22) reported a slightly higher VBIS incidence of 5.1% (3/59) of patients over a three-yr period. In that cohort, two patients with VBIS required lobectomy, while the other patient underwent early sequential balloon dilatation that resulted in good patency of the airway (22).…”

Section: Discussionmentioning

confidence: 95%

“…(22) reported a slightly higher VBIS incidence of 5.1% (3/59) of patients over a three‐yr period. In that cohort, two patients with VBIS required lobectomy, while the other patient underwent early sequential balloon dilatation that resulted in good patency of the airway (22).…”

Section: Discussionmentioning

confidence: 96%

“…There have been two small retrospective studies published in abstract form that described VBIS in lung transplant recipients (21,22). Over a 15-yr time period, Shah et al (21) found that 2% (7/344) of patients developed VBIS.…”

Section: Discussionmentioning

confidence: 99%

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Vanishing bronchus intermedius syndrome in a pediatric patient with cystic fibrosis after lung transplantation

Hayes

Mansour

2012

Pediatric Transplantation

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Hayes D Jr, Mansour HM. Vanishing bronchus intermedius syndrome in a pediatric patient with cystic fibrosis after lung transplantation. Abstract: Airway complications occur frequently after lung transplantation. Bronchial stenosis is the most frequently encountered complication with the most severe form of that being the vanishing bronchus intermedius syndrome (VBIS). This rare disorder has never been reported in the pediatric population. This is the first report of VBIS in a pediatric patient, specifically a 16‐yr‐old male patient with cystic fibrosis whose course was complicated by a lower airway infection with Aspergillus fumigatus. The VBIS responded to bronchoscopic balloon dilation and placement of an airway stent.

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Section: Discussionmentioning

confidence: 95%

Section: Discussionmentioning

confidence: 96%

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Vanishing bronchus intermedius syndrome in a pediatric patient with cystic fibrosis after lung transplantation

Hayes

Mansour

2012

Pediatric Transplantation

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“…Several treatment procedures including lobectomy, balloon dilatations, bronchoplasty with stent replacement, brachytherapy, electrocautery, and mitomycin application are suggested. [5][6][7] In a case series, Kesavan and associates evaluated 59 lung transplant patients and 3 of them developed VB complications. 6 Two of them underwent a lobectomy and 1 patient underwent sequential balloon dilatation.…”

Section: Figure 2 (A) Bronchial Narrowing On Left Lower Lobe Basal mentioning

confidence: 99%

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Yazicioğlu

Alıcı²,

Karaoğlanoğlu³

et al. 2018

Exp Clin Transplant

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We present a 22-year-old woman with Kartagener syndrome and scoliosis who died 112 days after single lung transplant. The classic thoracic involvement of situs inversus totalis and the asymmetric arrangement of the thoracic vascular structures might be a pitfall for surgeon. Anatomic obstacles have forced the surgeon to perform a single transplant. The period of primary graft dysfunction in a single transplanted lung patient was a challenge; supporting the patient with a high flow and long period of extracorporeal membrane oxygenation might lead to a vanishing bronchus. Immotile cilia, a feature of Kartagener syndrome, were another challenge and patient needed several daily aspiration bronchoscopies. Vanishing bronchus is a gradual process with high mortality rates; commonly, stenosis is at the non anastomotic bronchial tree because of insufficient nourishment of the bronchial cartilages. Several repeat bronchoscopic balloon dilatations accompanied with medical treatment were unsuccessful.

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“…A vanishing bronchus is a known airway complication after lung transplantation that typically is a slow and evolving process rather than an acute emergent situation. [ 1 – 4 ] We present a case of an acute vanishing left main bronchus occurring rapidly and resulting in hypoxic respiratory failure. The urgent placement of venovenous (VV) extracorporeal membrane oxygenation (ECMO) was required for respiratory support in order to perform airway dilation.…”

mentioning

confidence: 99%