Vaping during the <scp>COVID</scp>‐19 pandemic: <scp>NOT GOOD</scp>!!

Harrill, Willard C.

doi:10.1002/lio2.386

Cited by 2 publications

(3 citation statements)

References 3 publications

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“…McFadden et al found the frequency of hospitalization among COVID-19-positive vapers vs. COVID-19-positive non-vapers to be low, with a non-significant difference between the two groups with similar frequency results for ED visits [ 23 ]. Higher possibilities of contracting COVID-19 in vapers and smokers were postulated, but different studies could not settle this claim [ 8 , 20 ]. Possible mechanisms linking COVID-19 with smoking, including vaping, have been established by the ACE2 receptors.…”

Section: Reviewmentioning

confidence: 99%

“…In our study, similar to Usman et al, our results were not statistically significant to conclusively say, to be in agreement with other studies till date, that vapers might have lower odds of COVID-19 compared to non-smokers. There are elaborate mechanism pathways described by various authors regarding possible pulmonary epithelial damage resulting in the accentuation of COVID-19 from e-cigarette smoke including EVALI [ 6 , 8 , 26 ]. Tobacco products have been known to cause not just lung disease but also cancer, cardiovascular disease, diabetes, and diseases of the immune system [ 27 ].…”

Section: Reviewmentioning

confidence: 99%

“…Investigations were initiated during this time using animal models. One study suggested a possible increase in harmful effects from nicotine use in the form of e-cigarettes owing to an increase in ACE2 receptors in lung tissue, as it was found that this is one of the receptors that COVID-19 binds to [ 8 ]. In another study, it was found that e-cigarettes increase the inflammatory response in the lungs without having the appropriate repairing cascade of factors activated specifically by the alpha7 nicotinic acetylcholine receptor (nAChRα7).…”

Section: Introductionmentioning

confidence: 99%

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E-cigarette Use and Severe Coronavirus Disease 2019 (COVID-19) Outcomes: A Meta-Analysis

Valadez-Cuen,

Bhatt,

Mendez

et al. 2024

Cureus

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E-cigarettes have been known to cause varied poor health outcomes prior to coronavirus disease 2019 (COVID-19), but after the impact of COVID-19, evidence came out that was, in some instances, not as expected regarding the severity of COVID-19 among e-cigarette users (vapers). A meta-analysis was performed on the available evidence to comprehensively find the effect of COVID-19 on existing or past ecigarette users (vapers). The Meta-analysis of Observational Studies in Epidemiology (MOOSE) guidelines were used to perform this meta-analysis. PubMed was searched for observational studies that described outcomes after COVID-19 positivity from December 1, 2019, to December 2023. Medical Subject Headings (MeSH) keywords were used for searching the relevant studies highlighting the relationship between COVID-19 and e-cigarette users. Calculations for pooled prevalence, 95% confidence interval (95% CI), weights for current e-cigarette users and vapers, and outcomes (events) were made. To analyze the data, Review Manager V.5.4 was used. The I² statistic was used to assess statistical heterogeneity. The I² statistic of >50% was considered significant heterogeneity. The "leave-one-out" method was used for sensitivity analysis. Out of 3231 studies, four studies reported data on vaping and non-vaping status and composite outcomes, resulting in a sample size of 653 COVID-19-positive cases. The pooled prevalence of being COVID-19 positive, having symptoms, or visiting an emergency room was 7.78% (653/8392). COVID-19 patients with current vaping status had decreased odds of poor outcomes compared to non-smokers, with a pooled odds ratio (OR) of 0.09 (95% CI 0.00-2.42; p>0.05) with heterogeneity between studies (I²=99%, p=0.15). Because of difficulties related to data collection and other factors, this meta-analysis was unable to conclusively establish the correlation between e-cigarette usage and severe COVID-19 outcomes such as hospitalization, admission to the intensive care unit, and fatality. Additional research using more detailed data is necessary to fully understand this correlation.

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Section: Reviewmentioning

confidence: 99%

Section: Reviewmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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E-cigarette Use and Severe Coronavirus Disease 2019 (COVID-19) Outcomes: A Meta-Analysis

Valadez-Cuen,

Bhatt,

Mendez

et al. 2024

Cureus

View full text Add to dashboard Cite

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Symptoms COVID 19 Positive Vapers Compared to COVID 19 Positive Non-vapers

McFadden

Bornstein

Vassallo

et al. 2022

J Prim Care Community Health

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Objectives: The purpose of the present study was to assess and describe the severity of symptoms reported by Covid-19 positive patients who vaped (smoked e-cigarettes) when compared to those who did not vape or smoke at the time of the diagnosis of Covid-19. Methods: Patients from this study are from a well-characterized patient cohort collected at Mayo Clinic between March 1, 2020 and February 28, 2021; with confirmed COVID-19 diagnosis defined as a positive result on reverse-transcriptase–polymerase-chain-reaction (RT-PCR) assays from nasopharyngeal swab specimens. Among the 1734 eligible patients, 289 patients reported current vaping. The cohort of vapers (N = 289) was age and gender matched to 1445 covid-19 positive patients who did not vape. The data analyzed included: date of birth, gender, ethnicity, race, marital status, as well as lifestyle history such as vaping and smoking and reported covid-19 symptoms experienced. Results: A logistic regression analysis was performed separately for each symptom using generalized estimating equations (GEE) with robust variance estimates in order to account for the 1:5 age, sex, and race matched set study design. Patients who vaped and developed Covid-19 infection were more likely to have chest pain or tightness (16% vs 10%, vapers vs non vapers, P = .005), chills (25% vs 19%, vapers vs non vapers, P = .0016), myalgia (39% vs 32%, vapers vs non vapers, P = .004), headaches (49% vs 41% vapers vs non vapers, P = .026), anosmia/dysgeusia (37% vs 30%, vapers vs non vapers, P = .009), nausea/vomiting/abdominal pain (16% vs 10%, vapers vs non vapers, P = .003), diarrhea (16% vs 10%, vapers vs non vapers, P = .004), and non-severe light-headedness (16% vs 9%, vapers vs non vapers, P < .001). Conclusion: Vapers experience higher frequency of covid-19 related symptoms when compared with age and gender matched non-vapers. Further work should examine the impact vaping has on post-covid symptom experience.

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Vaping during the COVID‐19 pandemic: NOT GOOD!!

Abstract: Time flies when you are having fun…. And even more so when you are not. Faced with the evolving COVID-19 pandemic, it is easy to

Cited by 2 publications

References 3 publications

E-cigarette Use and Severe Coronavirus Disease 2019 (COVID-19) Outcomes: A Meta-Analysis

E-cigarette Use and Severe Coronavirus Disease 2019 (COVID-19) Outcomes: A Meta-Analysis

Symptoms COVID 19 Positive Vapers Compared to COVID 19 Positive Non-vapers

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