Abstract. The Guinea Coast is the southern part of the West African continent. Its summer rainfall variability mostly occurs on interannual timescales and is highly influenced by the sea surface temperature (SST) variability in the eastern equatorial Atlantic, which is the centre of action of the Atlantic Niño mode. Using both historical and scenario (SSP5–8.5) simulations from 31 general circulation models (GCMs) participating in the sixth phase of the Coupled Model Intercomparison Project (CMIP6), we first show that these models present a wet bias during boreal summer. This bias is associated with overly high mean boreal summer SSTs in the eastern equatorial and south Atlantic regions. Next, we analyse the near-term, mid-term and long-term changes of the Atlantic Niño relative to the present-day situation, in a climate with a high anthropogenic emission of greenhouse gases. We find a gradual decrease in the equatorial Atlantic SST anomalies associated with the Atlantic Niño in the future. This result reflects a possible reduction of the Atlantic Niño variability in the future due to a weakening of the Bjerknes feedback over the equatorial Atlantic. In a warmer climate, an anomalous higher sea level pressure in the western equatorial Atlantic relative to the eastern equatorial Atlantic weakens the climatological trade winds over the equatorial Atlantic. As a result, the eastern equatorial Atlantic thermocline is deeper and responds less to the Atlantic Niño events. Among the models that simulate a realistic rainfall pattern associated with the Atlantic Niño in the present-day climate, there are 12 GCMs which project a long-term decrease in the Guinea Coast rainfall response related to the Atlantic Niño. In these models, the zonal 850 hPa wind response to the Atlantic Niño over the equatorial Atlantic is strongly attenuated in the future climate. We also find that 12 other GCMs show no robust change in the patterns associated with the Atlantic Niño. There is a higher confidence in the mid-term and long-term reduction of the rainfall associated with the Atlantic Niño over the Atlantic Ocean than over the Guinea Coast. We also found a projected decrease in the convection associated with the Atlantic Niño in the majority of the models.