Variability of Ultrasonic Pachometry

Gordon, Adam; Boggess, Eve A.; Molinari, Joseph F.

doi:10.1097/00006324-199003000-00003

Cited by 66 publications

(32 citation statements)

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“…We found that the Topcon specular microscope provided measurements that were, on average, 32 µm less than those from the ultrasound pachymeter. Other studies have documented the variability of different types of pachymetric data 9 ; corneal thickness measurements from a Haag Streit (Bern, Switzerland) optical pachymeter were also found to be significantly less than ultrasound pachymetric measurements. 10 Despite the difference between the values provided by the instruments in our study, however, the similarities in the overall ranges and SEMs point to similar reproducibility for the 2 instruments.…”

Section: Commentmentioning

confidence: 94%

Corneal Thickness Measurements With the Topcon SP-2000P Specular Microscope and an Ultrasound Pachymeter

Bovelle¹

1999

Arch Ophthalmol

113

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Section: Commentmentioning

confidence: 94%

Corneal Thickness Measurements With the Topcon SP-2000P Specular Microscope and an Ultrasound Pachymeter

Bovelle¹

1999

Arch Ophthalmol

113

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“…Nowadays, measurements of corneal thickness are easier, more reproducible and more accurate when using ultrasonic pachymeters [first developed by Kremer (1980) with the advent of radial keratotomy] (Rapuano 1993), computer-assisted laser pachymetry and laser Doppler interferometry (Gritz & McDonnell 1990;Hitzenberger et al 1992;Rapuano et al 1993). Gordon et al (1990) found good reproducibility of ultrasonic central corneal thickness (CCT) measurements that also were found to be less variable and more reproducible by Higgins et al (1993). Thus, knowing the normal value of the CCT in newborn babies can be used as a reference in the early diagnosis and control of corneal oedema in some ocular disease such as primary congenital glaucoma.…”

Section: Introductionmentioning

confidence: 94%

Central corneal thickness in full‐term Saudi newborns

Rushood

Zahrani

Khamis

et al. 2012

Acta Ophthalmologica

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ABSTRACT.Purpose: To establish a standard of normal central corneal thickness (CCT) in normal full-term Saudi newborn. These values could be used as a reference in the early diagnosis and control of the fairly common primary congenital glaucoma in Saudi newborns. Methods: The CCT was measured in 100 normal full-term Saudi newborns (200 eyes) during the first 6 days of the postnatal period. All measurements were carried out by one investigator using ultrasonic pachymeter DGH-1000. Results: The mean CCT of 200 eyes (right and left) was 616 ± 61 lm. The mean CCT of the right and left eyes was similar (CCTRE was 617 ± 62 lm, and mean CCTLE was 616 ± 60 lm), with no statistically significant difference (p = 0.417). The mean CCT for males was 631 ± 66 lm and for females 600 ± 50 lm. This difference was statistically significant (p = 0.01). The mean CCT decreases significantly by age [day-1: 626 ± 65 lm, day-2: 601 ± 48 lm and day-3: 574 ± 45 lm (p = 0.049)]. No correlations were found between CCT and gestational age, birth weight, birth length and head circumference. Conclusion: The average CCT in full-term Saudi newborns was found to be 616 ± 61 lm. The mean CCT in males was significantly higher than in females. There was no correlation between CCT and gestational age, birth weight, birth length and head circumference. There were borderline significant differences between CCT in 1-day-, 2-day-, and 3-day-old babies.

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“…22,23 To provide high-precision CCT measurements with low interobserver and intersession variability, the measurements in this study were performed using ACMaster, which is based on the principle of partial coherence interferometry as reported previously. 19,[24][25][26] To our knowledge, only 1 study 16 described 9 cases of irreversible corneal decompensation after use of dorzolamide.…”

Section: Commentmentioning

confidence: 99%

Effect of Dorzolamide Hydrochloride on Central Corneal Thickness in Humans With Cornea Guttata

Wirtitsch

Findl²,

Heinzl³

et al. 2007

Arch Ophthalmol

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To investigate the effect of dorzolamide hydrochloride on central corneal thickness in humans with cornea guttata.Design: Randomized, placebo-controlled, doublemasked, 2-drug crossover study with 10 patients with cornea guttata and 10 healthy controls, who had mean endothelial cell counts of 988 and 2377 cells/mm 2 , respectively. Study medications were 2% dorzolamide and placebo drops applied 3 times a day for 4 weeks. Central corneal thickness measurements using ACMaster (Carl Zeiss Meditec AG, Jena, Germany) and Goldmann applanation tonometry were performed at baseline, 1 day, 1 week, and 4 weeks. Results:The mean increases in central corneal thickness after 4 weeks in eyes with cornea guttata treated with dorzolamide and placebo were 26.3 µm (95% confidence interval, 8.8 to 43.7) and 3.3 µm (95% confidence interval, −0.5 to 7.1), respectively. No statistically significant changes were measured in the healthy control group. Dorzolamide caused a significant decrease in intraocular pressure (PϽ.01) while placebo did not cause significant changes (P =.50). Conclusion:Application of dorzolamide for 4 weeks resulted in a statistically significant increase in central corneal thickness in patients with compromised corneal endothelium. These results indicate that patients with corneal endothelial problems receiving dorzolamide therapy should be monitored.

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Variability of Ultrasonic Pachometry

Cited by 66 publications

References 0 publications

Corneal Thickness Measurements With the Topcon SP-2000P Specular Microscope and an Ultrasound Pachymeter

Corneal Thickness Measurements With the Topcon SP-2000P Specular Microscope and an Ultrasound Pachymeter

Central corneal thickness in full‐term Saudi newborns

Effect of Dorzolamide Hydrochloride on Central Corneal Thickness in Humans With Cornea Guttata

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