Variable-focusing microlens with microfluidic chip

Chen, Jackie; Wang, Weisong; Fang, Ji; Varahramyan, Kody

doi:10.1088/0960-1317/14/5/003

Cited by 168 publications

(97 citation statements)

References 12 publications

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“…In addition, HCG lenses covering a large range of numerical apertures have been fabricated and characterized, highlighting the wide range of parameters available with these lenses. Due to the high index contrast and planarity, HCG lenses are very suitable for applications in microfluidics, as their performance will not deteriorate in an aqueous environment, unlike conventional microlenses based on polymers 15 or glass. 16 The feasibility of producing arrays of HCG microlenses is also straightforward.…”

Section: Resultsmentioning

confidence: 99%

Focusing with planar microlenses made of two-dimensionally varying high contrast gratings

et al. 2014

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Abstract. We report on the focusing performance of reflective two-dimensionally varying high contrast grating lenses based on silicon. The combination of their subwavelength nature and their high refractive index contrast makes it possible to create highly tolerant and planar microlenses. We used a rigorous mathematical code to design the lenses and verified their performance with finite element simulations. We also investigated the effects of grating thickness, angle, and wavelength of incidence in these simulations. Experimentally, we show the evolution of the beam profile along the optical axis for a lens with a high (0.37) numerical aperture. We have explored a wide range of numerical apertures (0.1-0.93) and show that the lenses behave as expected across the full range. Our analyses demonstrate the large design flexibility with which these lenses can be made along with ease of fabrication and potential for a number of applications in micro-optics.

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Section: Resultsmentioning

confidence: 99%

Focusing with planar microlenses made of two-dimensionally varying high contrast gratings

et al. 2014

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“…(1,2) There have been extensive trials to achieve liquid lenses with deformable geometric shapes employing various driving mechanisms. (3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16) They include diverse flexible-membrane lenses, electrowetting-based lenses, and dielectrophoretic lenses. (17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29) Rather than modulating the geometric shape of the lens, one can also choose to vary the refractive index of the lens material.…”

Section: Introductionmentioning

confidence: 99%

Miniature Solid Tunable Lenses and Their Applications: A Review

Yongchao¹,

Siong²,

Guangya³

2017

Sensors and Materials

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We present a systematic review of solid tunable lenses based on the Alvarez-Lohmann principle, which mainly focuses on the optimization, miniaturization, and integration of such solid tunable lenses in miniature applications. The progress of the modelling and design methods of such solid tunable lenses for optimum performance is summarized first. The development of various solid tunable lenses achieved using diverse driving mechanisms and different optimization methods is then illustrated by examples from current literature. The mechanisms, performance, and practicability of all these prototypes are presented in detail. The applications of such solid tunable lenses in miniature imaging systems are finally reviewed. Discussions of the problems and bottlenecks encountered in current research work and perspectives for future work in this field are given.

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“…Research efforts towards low cost, compact imaging systems have focused on utilizing microlenses [7][8][9][10] and microlens arrays [11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26] optofluidic microscope [27,28] or even tomographic imaging methods [29,30]. Although these approaches demonstrated high-resolution imaging, they typically lack the flexibility and versatility of a stereo microscope where the user can easily adjust the focus and magnification or the illumination conditions depending on the sample that is being imaged.…”

Section: Introductionmentioning

confidence: 99%

An Optofluidic Lens Array Microchip for High Resolution Stereo Microscopy

2014

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Abstract:We report the development of an add-on, chip-based, optical module-termed the Microfluidic-based Oil-immersion Lenses (μOIL) chip-which transforms any stereo microscope into a high-resolution, large field of view imaging platform. The μOIL chip consists of an array of ball mini-lenses that are assembled onto a microfluidic silicon chip. The mini-lenses are made out of high refractive index material (sapphire) and they are half immersed in oil. Those two key features enable submicron resolution and a maximum numerical aperture of ~1.2. The μOIL chip is reusable and easy to operate as it can be placed directly on top of any biological sample. It improves the resolution of a stereo microscope by an order of magnitude without compromising the field of view; therefore, we believe it could become a versatile tool for use in various research studies and clinical applications.

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Variable-focusing microlens with microfluidic chip

Cited by 168 publications

References 12 publications

Focusing with planar microlenses made of two-dimensionally varying high contrast gratings

Focusing with planar microlenses made of two-dimensionally varying high contrast gratings

Miniature Solid Tunable Lenses and Their Applications: A Review

An Optofluidic Lens Array Microchip for High Resolution Stereo Microscopy

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