Variable Rate Iv Infusion of Morphine and Haemodynamic Response to Laryngoscopy and Tracheal Intubation

Abstract

Lt Col PM VELANKAR*. Surg Lt Cdr MS SAlfi+. Brig SP MEHTA (Retd)' ABSTRAcr Haemodynamic response. to laryngoscopy and tracheal intubation was studied in two groups of 45 patients each. Group I patients received variable rate infusion of morphine for 30 minutes followed by intravenous (IV) bolus dose of diazepam. Group n patients received intramuscular morphine as preanaesthetic premedication and preinduction IV bolus dose of diazepam. The method of fnductien of GA was same in both the groups. Systolic and diastolic blood pressure (SBP and DBP) mean arterial pressure and pulse-rate were recorded at intubatiDn and at different time intervals upto 10 minutes after intubation. In group I patients, there was no statistically significant increase in pulse-rate and SBP fDllowing Intubation but transient significant increase in DBP.In group n patients. there was statistically significant increase in pulse-rate. SBP and DBP upto 3 minutes post-intubation. Thus IV infusion of merpbtne in combination with IV bDlus dose ef diazepam proved more effective in attenuating haemDdynamic response to tracheal intubatiDn.