In several projects in computational biology (CB), bioinformatics, health informatics(HI), precision medicine(PM) and precision agriculture(PA) machine learning(ML) has become a primary resource. In this paper we studied the use of machine learning in the development of computational methods for top five research aeras. The last few years have seen an increased interest in Artificial Intelligence (AI), comprehensive ML and DL techniques for computational method development. Over the years, an enormous amount of research has been biomedical scientists still don’t have more knowledge to handle a biomedical projects efficiently and may, therefore, adopt wrong methods, which can lead to frequent errors or inflated tests. Healthcare has become a fruitful ground for artificial intelligence (AI) and machine learning due to the increase in the volume, diversity, and complexity of data (ML). Healthcare providers and life sciences businesses already use a variety of AI technologies. The review summarizes a traditional machine learning cycle, several machine learning algorithms, various techniques to data analysis, and effective use in five research areas. In this comprehensive review analysis, we proposed 10 ten rapid and accurate practices to use ML techniques in health informatics, bioinformatics, computational and systems biology, precision medicine and precision agriculture, avoid some common mistakes that we have observed several hundred times in several computational method works.