Variables influencing the frictional behaviour of in vivo human skin

Veijgen, N.K.; Masen, Marc Arthur; Heide, Emile van der

doi:10.1016/j.jmbbm.2013.02.009

Cited by 41 publications

(35 citation statements)

References 48 publications

(139 reference statements)

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“…The main factor limiting the development of predictive models is that skin-object interaction is a highly nonlinear and multifactorial system [31,33]. The parameters that affect the interaction behaviour of skin encompass the geometrical, mechanical and biophysical domains and, next to application-related interaction parameters such as contact pressures and sliding velocities, include the local microclimate (temperature and humidity) as well as individual's characteristics (e.g.…”

Section: Introductionmentioning

confidence: 99%

Skin Microstructure is a Key Contributor to Its Friction Behaviour

et al. 2016

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Due to its multifactorial nature, skin friction remains a multiphysics and multiscale phenomenon poorly understood despite its relevance for many biomedical and engineering applications (from superficial pressure ulcers, through shaving and cosmetics, to automotive safety and sports equipment). For example, it is unclear whether, and in which measure, the skin microscopic surface topography, internal microstructure and associated nonlinear mechanics can condition and modulate skin friction. This study addressed this question through the development of a parametric finite element contact homogenisation procedure which was used to study and quantify the effect of the skin microstructure on the macroscopic skin frictional response. An anatomically realistic two-dimensional image-based multilayer finite element model of human skin was used to simulate the sliding of rigid indenters of various sizes over the skin surface. A corresponding structurally idealised multilayer skin model was also built for comparison purposes. Microscopic friction specified at skin asperity or microrelief level was an input to the finite element computations. From the contact reaction force measured at the sliding indenter, a homogenised (or apparent) macroscopic friction was calculated. Results demonstrated that the naturally complex geometry of the skin microstructure and surface topography alone can play as significant role in modulating the deformation component of macroscopic friction and can significantly increase it. This effect is further amplified as the ground-state Young's modulus of the stratum corneum is increased (for example, as a result of a dryer environment). In these conditions, the skin microstructure is a dominant factor in the deformation component of macroscopic friction, regardless of indenter size or specified local friction properties. When the skin is assumed to be an assembly of nominally flat layers, the resulting global coefficient of friction is reduced with respect to the local one. This seemingly counter-intuitive effect had already been demonstrated in a recent computational study found in the literature. Results also suggest that care should be taken when assigning a coefficient of friction in computer simulations, as it might not reflect the conditions of microscopic and macroscopic friction one intends to represent. The modelling methodology and simulation tools developed in this study go beyond what current analytical models of skin friction can offer: the ability to

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Section: Introductionmentioning

confidence: 99%

Skin Microstructure is a Key Contributor to Its Friction Behaviour

et al. 2016

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“…Given that the skin is the human body's interface to the external environment, these results have implications for a variety of mechanical and/or mechanobiological processes (Limbert and Simms, 2013) across many domains of application including skin tribology in general (van Kuilenburg et al, 2013a, b;Veijgen et al, 2013b), pressure sores (Brand, 2006) and wound healing ).…”

Section: Discussionmentioning

confidence: 99%

A mechanistic insight into the mechanical role of the stratum corneum during stretching and compression of the skin

Leyva-Mendivil

Page

Bressloff

et al. 2015

Journal of the Mechanical Behavior of Biomedical Materials

109

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A mechanistic insight into the mechanical role of the stratum corneum during stretching and compression of the skin. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting galley proof before it is published in its final citable form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.www.elsevier.com/locate/jmbbm 1 A mechanistic insight into the mechanical role of the stratum corneum during stretching and compression of the skin. AbstractThe study of skin biophysics has largely been driven by consumer goods, biomedical and cosmetic industries which aim to design products that efficiently interact with the skin and/or modify its biophysical properties for health or cosmetic benefits. The skin is a hierarchical biological structure featuring several layers with their own distinct geometry and mechanical properties. Up to now, no computational models of the skin have simultaneously accounted for these geometrical and material characteristics to study their complex biomechanical interactions under particular macroscopic deformation modes.The goal of this study was, therefore, to develop a robust methodology combining histological sections of human skin, image-processing and finite element techniques to address fundamental questions about skin mechanics and, more particularly, about how macroscopic strains are transmitted and modulated through the epidermis and dermis. The work hypothesis was that, as skin deforms under macroscopic loads, the stratum corneum does not experience significant strains but rather folds/unfolds during skin extension/compression.A sample of fresh human mid-back skin was processed for wax histology. Sections were stained and photographed by optical microscopy. The multiple images were stitched together to produce a larger region of interest and segmented to extract the geometry of the stratum corneum, viable epidermis and dermis. From the segmented structures a 2D finite element mesh of the skin composite model was created and geometrically non-linear plane-strain finite element analyses were conducted to study the sensitivity of the model to variations in mechanical properties.The hybrid experimental-computational methodology has offered valuable insights into the simulated mechanics of the skin, and that of the stratum corneum in particular, by providing qualitative and quantitative information on strain magnitude and distribution. Through a complex non-linear interplay, the geometry and mechanical characteristics of the skin layers (and their relative balance), play a critical role in conditioning the skin mechanical response to macroscopic in-plane compression and extension. Topographical features of the skin surface such as furrows were shown to act as an efficient means to deflec...

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“…Geometrical alterations of the the skin surface (e.g. wrinkles), particularly at the microscopic scale, is likely to modulate these effects [17,35,151,152] via finite deformations and associated fluctuations in effective contact area. Geometrical effects on asperities (i.e.…”

Section: Skin Friction Is Modulated By Age-dependent Mechanical and Smentioning

confidence: 99%

Biotribology of the ageing skin—Why we should care

et al. 2019

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Ageing of populations has emerged as one of the most pressing societal, economic and healthcare challenges currently facing most nations across the globe. The ageing process itself results in degradation of physiological functions and biophysical properties of organs and tissues, and more particularly those of the skin. Moreover, in both developed and emerging economies, population ageing parallels concerning increases in lifestyleassociated conditions such as Type 2 diabetes, obesity and skin cancers. When considered together, these demographic trends call for even greater urgency to find clinical and engineering solutions for the numerous age-related deficits in skin function. From a tribological perspective, detrimental alterations of skin bioph ysical properties with age have fundamental consequences on how one interacts with the body's inner and outer environments. This stems from the fact that, besides being the largest organ of the human body, and also nearly covering its entirety, the skin is a multifunctional interface which mediates these interactions. The aim of this paper is to present a focused review to discuss some of the consequences of skin ageing from the viewpoint of biotribology, and their implications on health, well -being and human activities. Current and future research questions/challenges associated with biotribology of the ageing ski n are outlined. They provide the background and motivation for identifying future lines of research that could be taken up by the biotribology and biophysics communities.

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Variables influencing the frictional behaviour of in vivo human skin

Cited by 41 publications

References 48 publications

Skin Microstructure is a Key Contributor to Its Friction Behaviour

Skin Microstructure is a Key Contributor to Its Friction Behaviour

A mechanistic insight into the mechanical role of the stratum corneum during stretching and compression of the skin

Biotribology of the ageing skin—Why we should care

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