Variación en el gen del transportador de serotonina y alucinaciones auditivas en la psicosis

Enormous efforts have been made to unveil the etiology of auditory hallucinations (AHs), and multiple genetic and neural factors have already been shown to have their own roles. Previous studies have shown that AHs in schizophrenia vary from those in other disorders, suggesting that they have unique features and possibly distinguishable mechanisms worthy of further investigation. In this review, we intend to offer a comprehensive summary of current findings related to AHs in schizophrenia from aspects of genetics and transcriptome, neurophysiology (neurometabolic and electroencephalogram studies), and neuroimaging (structural and functional magnetic resonance imaging studies and transcriptome–neuroimaging association study). Main findings include gene polymorphisms, glutamate level change, electroencephalographic alterations, and abnormalities of white matter fasciculi, cortical structure, and cerebral activities, especially in multiple regions, including auditory and language networks. More solid and comparable research is needed to replicate and integrate ongoing findings from multidimensional levels.

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Variación en el gen del transportador de serotonina y alucinaciones auditivas en la psicosis

Abstract: por la lectura y revisión de una versión preliminar de este trabajo, y a I. Toirac, A. Tolosa y J.L. Ivorra, por su valiosa ayuda en la extracción del ADN. Aceptado tras revisión externa: 21.09.09.

Cited by 2 publications

References 48 publications

Génétique des hallucinations : des voix pas sans gène !

Génétique des hallucinations : des voix pas sans gène !

The Etiology of Auditory Hallucinations in Schizophrenia: From Multidimensional Levels

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