Variant hemoglobin (Hb hope) may enhance glycosylated hemoglobin (HbA1c) results of cation exchange high performance liquid chromatography

Kapoor, A. K.

doi:10.18535/jmscr/v6i9.129

jmscr

2018

DOI: 10.18535/jmscr/v6i9.129

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Variant hemoglobin (Hb hope) may enhance glycosylated hemoglobin (HbA1c) results of cation exchange high performance liquid chromatography

A. K. Kapoor¹

Abstract: Variant hemoglobin (Hb hope) may enhance glycosylated hemoglobin (HbA1c) results of cation exchange high performance liquid chromatography

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2021

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Pitfalls in Estimation of Glycosylated Hemoglobin

Mathew

Rajagopal

Wasir

2021

Journal of Diabetology

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Hemoglobin (Hb) Hope is a rare Hb variant which is clinically silent but causes spuriously high glycated hemoglobin (HbA1c). We report a case of a 45-year-old gentleman, planned for elective total hip replacement, who presented with very high HbA1c with normal blood glucose and fructosamine levels. With the suspicion of erroneous HbA1c, an Hb electrophoresis was done, and he was found to have a rare hemoglobin variant called Hb Hope. We also reviewed almost all case reports of Hb Hope variant causing spuriously high HbA1c levels from India.

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Pitfalls in Estimation of Glycosylated Hemoglobin

Mathew

Rajagopal

Wasir

2021

Journal of Diabetology

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Variant hemoglobin (Hb hope) may enhance glycosylated hemoglobin (HbA1c) results of cation exchange high performance liquid chromatography

Abstract: Variant hemoglobin (Hb hope) may enhance glycosylated hemoglobin (HbA1c) results of cation exchange high performance liquid chromatography

Cited by 1 publication

References 5 publications

Pitfalls in Estimation of Glycosylated Hemoglobin

Pitfalls in Estimation of Glycosylated Hemoglobin

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