Variants in the TERT Gene Increase the Occurrence of Solar Lentigines by Modifying Telomerase Expression Exclusively in the Skin

No increase of CD8+ TEMRA cells in the blood of healthy adults at high genetic risk of Alzheimer's disease

“…Jan Homann 1 David Goldeck 2,3 Olena Ohlei 4 Valerija Dobricic 4 Johanna Drewelies 5 Ilja Demuth 5,6 Graham Pawelec 7,8…”

“…Detailed methods can be found in the Supplementary methods . Briefly, quality‐controlled genome‐wide single nucleotide polymorphism (SNP) data ( n = 7,536,015) 4 and CD8+ TEMRA cell proportions of total CD8+ T cells in blood (Table S1 ) 5 were available for 370 cognitively healthy individuals comprising a group of young adults ( n = 120, mean age: 29 years, range 23–35) and a group of older people ( n = 250, mean age: 69 years, range 60–82). All participants were recruited as part of the Berlin Aging Study II (BASE‐II), a multi‐institutional and multidisciplinary project aimed to characterize the individual changes of healthy participants (at the time of recruitment) in the aging process.…”