Variants of Takotsubo syndrome in the perioperative period: A review of potential mechanisms and anaesthetic implications

Gibson, Lauren E.; Klinker, Mark R.; Wood, Malissa J.

doi:10.1016/j.accpm.2020.01.010

Cited by 10 publications

(16 citation statements)

References 52 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…ont déjà discuté de la variété non apicale de syndrome de Takotsubo périopératoire. 9 La forte prévalence de malignité dans le syndrome de Takotsubo périopératoire (38 %) rapportée par Garcia Guzzo et coll. 6 est nouvelle et, bien que l'association entre malignité et syndrome de Takotsubo soit maintenant bien reconnue, cette association n'a pas encore été rapportée spécifiquement en cas de syndrome de Takotsubo périopératoire.…”

Section: Management Ofunclassified

“…Gibson et al previously discussed the non-apical variety of perioperative TS. 9 The high prevalence of malignancy in perioperative TS (38%) reported by Garcia Guzzo et al 6 is novel, and although the association of malignancy with TS is now well-recognized, this association has not previously been reported with perioperative TS specifically. In the International Takotsubo Registry, 16.6% of patients had diagnosis of malignancy, which was more frequently precipitated by physical stressors.…”

mentioning

confidence: 90%

See 1 more Smart Citation

Shining a light on perioperative Takotsubo syndrome

Hessel

2021

Can J Anesth/J Can Anesth

View full text Add to dashboard Cite

Section: Management Ofunclassified

mentioning

confidence: 90%

Shining a light on perioperative Takotsubo syndrome

Hessel

2021

Can J Anesth/J Can Anesth

View full text Add to dashboard Cite

“…21 Alpha-2 agonists, such as dexmedetomidine and clonidine, may be beneficial to prevent recurrence in at-risk patients by reducing sympathetic outflow. 22 In conclusion, we describe the first known case of a postmenopausal female with postoperative CA after ureteral stenting due to TC. We emphasize the importance of maintaining a high suspicion of TC perioperatively, and we hope to increase awareness of the various risk factors for this syndrome.…”

Section: Discussionmentioning

confidence: 82%

“… 21 Alpha-2 agonists, such as dexmedetomidine and clonidine, may be beneficial to prevent recurrence in at-risk patients by reducing sympathetic outflow. 22 …”

Section: Discussionmentioning

confidence: 99%

Takotsubo cardiomyopathy as an overlooked cause of cardiac arrest in a patient undergoing ureteral stenting: a case report and literature review

Liu

et al. 2022

J Int Med Res

View full text Add to dashboard Cite

Takotsubo cardiomyopathy (TC) is a rare disease with unclear etiology that is characterized by wall motion abnormalities of the left ventricle. We report a 64-year-old woman who presented with cardiac arrest 6 hours after ureteral stenting, with no history of heart disease. Notably, she had a urinary tract infection preoperatively. TC was diagnosed with characteristic apical ballooning on the left ventriculogram. The hemodynamics and cardiac function recovered quickly within 1 day after conservative treatment and controlling the infection. TC should be considered when a patient presents with decreased cardiac function after ureteral stenting, especially in patients with potential concurrent infection. A review of the literature documenting cases of TC related to urological surgery in the past decade was conducted using PubMed. The results were summarized in a table.

show abstract

“…The exact pathophysiological mechanisms remained unclear, but many researchers have suggested that the surgery was an important trigger for Takotsubo cardiomyopathy ( 29 ). The broader scope of surgical trauma and longer operation time, the more apparent sympathetic activation that patients will encounter, and thereby the incidence of Takotsubo cardiomyopathy will be higher during the perioperative period ( 30 ). This cardiovascular complication has received less attention in previous studies, but its incidence was not rare, and the perniciousness could not be ignored in our investigation.…”

Section: Discussionmentioning

confidence: 99%

Development and Validation of Predictive Model—HASBLAD Score—For Major Adverse Cardiovascular Events During Perioperative Period of Non-cardiac Surgery: A Single Center Experience in China

Zhao

Shang

Cai

et al. 2022

Front. Cardiovasc. Med.

View full text Add to dashboard Cite

BackgroundMajor adverse cardiovascular events (MACEs) represent a significant reason of morbidity and mortality in non-cardiac surgery during perioperative period. The prevention of perioperative MACEs has always been one of the hotspots in the research field. Current existing models have not been validated in Chinese population, and have become increasingly unable to adapt to current clinical needs.ObjectivesTo establish and validate several simple bedside tools for predicting MACEs during perioperative period of non-cardiac surgery in Chinese hospitalized patients.DesignWe used a nested case-control study to establish our prediction models. A nomogram along with a risk score were developed using logistic regression analysis. An internal cohort was used to evaluate the performance of discrimination and calibration of these predictive models including the revised cardiac risk index (RCRI) score recommended by current guidelines.SettingPeking University Third Hospital between January 2010 and December 2020.PatientsTwo hundred and fifty three patients with MACEs and 1,012 patients without were included in the training set from January 2010 to December 2019 while 38,897 patients were included in the validation set from January 2020 and December 2020, of whom 112 patients had MACEs.Main Outcome MeasuresThe MACEs included the composite outcomes of cardiac death, non-fatal myocardial infarction, non-fatal congestive cardiac failure or hemodynamically significant ventricular arrhythmia, and Takotsubo cardiomyopathy.ResultsSeven predictors, including Hemoglobin, CARDIAC diseases, Aspartate aminotransferase (AST), high Blood pressure, Leukocyte count, general Anesthesia, and Diabetes mellitus (HASBLAD), were selected in the final model. The nomogram and HASBLAD score all achieved satisfactory prediction performance in the training set (C statistic, 0.781 vs. 0.768) and the validation set (C statistic, 0.865 vs. 0.843). Good calibration was observed for the probability of MACEs in the training set and the validation set. The two predictive models both had excellent discrimination that performed better than RCRI in the validation set (C statistic, 0.660, P < 0.05 vs. nomogram and HASBLAD score).ConclusionThe nomogram and HASBLAD score could be useful bedside tools for predicting perioperative MACEs of non-cardiac surgery in Chinese hospitalized patients.

show abstract

Variants of Takotsubo syndrome in the perioperative period: A review of potential mechanisms and anaesthetic implications

Cited by 10 publications

References 52 publications

Shining a light on perioperative Takotsubo syndrome

Shining a light on perioperative Takotsubo syndrome

Takotsubo cardiomyopathy as an overlooked cause of cardiac arrest in a patient undergoing ureteral stenting: a case report and literature review

Development and Validation of Predictive Model—HASBLAD Score—For Major Adverse Cardiovascular Events During Perioperative Period of Non-cardiac Surgery: A Single Center Experience in China

Contact Info

Product

Resources

About