Variation in Total Polyphenolics Contents of Aerial Parts of Potentilla Species and Their Anticariogenic Activity

Abstract

The aerial parts of selected Potentilla species (P. anserina, P. argentea, P. erecta, P. fruticosa, P. grandiflora, P. nepalensis, P. norvegica, P. pensylvanica, P. crantzii and P. thuringiaca) were investigated in order to determine their contents of polyphenolic compounds. The results showed that P. fruticosa has relatively high concentrations of tannins (167.3 ± 2.0 mg/g dw), proanthocyanidins (4.6 ± 0.2 mg/g dw) and phenolic acids (16.4 ± 0.8 mg/g dw), as well as flavonoids (7.0 ± 1.1 mg/g dw), calculated as quercetin. Furthermore, we investigated the in vitro inhibitory effects of aqueous extracts from these species against cariogenic Streptococcus spp. strains. It was found that the tested samples moderately inhibit the growth of oral streptococci. However, all the preparations exhibited inhibitory effects on water-insoluble α-(1→3)-, α-(1→6)-linked glucan (mutan) and artificial dental plaque formation. The extract from P. fruticosa showed the highest anti-biofilm activities, with minimum mutan and biofilm inhibition concentrations of 6.25–25 and 50–100 µg/mL, respectively. The results indicate that the studied Potentilla species could be a potential plant material for extracting biologically active compounds, and could become a useful supplement for pharmaceutical products as a new anticariogenic agent in a wide range of oral care products.

Expression of flavonoid biosynthesis genes vis-à-vis rutin content variation in different growth stages of Fagopyrum species

“…Rutin is one of the important flavonoids, providing protection against reactive oxygen species and having various pharmacological properties. The flavonoid content variation within species was studied in different plants like barrenwort, potentilla, ginger and citrus (Ghafar et al, 2010;Tomczyk et al, 2010;Quan et al, 2010). Rutin content has been quantified in various plants Eucalypus, amaranthus, apple, cherry, etc.…”

“…Rutin content was reported to be maximal in flowers of buckwheat (Wagenbreth et al, 1996). The flavonoid content variation has been reported in other plants, such as in barrenwort, potentilla, peanuts and citrus (Ghafar et al, 2010;Tomczyk et al, 2010;Quan et al, 2010).…”

Efficacy of a Kalanchoe gastonis-bonnieri extract to control bacterial biofilms and dental calculus in dogs

“…Phenolic-rich plant extracts and fractions have shown anti-plaque and anticariogenic activity in many studies (Yanagida et al 2000, Thimothe et al 2007, Tomczyk et al 2010, Yano et al 2012, Tomczyk et al 2013. In some of them, it was possible to establish a positive correlation between the phenolic content and anti-plaque activity (Tomczyk et al 2011, Yano et al 2012.…”

Phytochemical Screening and Gc-MS Analysis of Methanolic Extract of Bombax Ceiba Bark

“…Numerous reports available on phenolic compounds have demonstrated their usefulness in exhibiting potential biological activities such as antioxidant, antidiabetic, hepatoprotective, anti-inflammatory, antimicrobial, anticancer 17 etc. Flavonoids and tannins are considered to be the most promising polyphenolic compounds among plant secondary metabolites 18 . Therefore, based on the phytochemical screening results, the total phenolic and flavonoid contents of methanolic extract of Bombax ceiba bark was estimated.…”