Variation of Andrographolide Content in Andrographis paniculata from Different Sites of Balaghat Region of Jabalpur (M.P.)

Abstract

Aim:The main objective of this investigation was to show the variation of Andrographolide content in Andrographis paniculata from thirty seven different sites of Balaghat (Jabalpur MP) region. Methodology:In order to study the variation in andrographolide content, plant material was collected from different sites and were analyzed through quick and accurate HPLC chromatographic method using C-18 column (4.6 x 250 mm, 5µ particle size). Result and Discussion:The average andrographolide content varied from 0.01 to 1.2%. Highest percent of andrographolide in Andrographis paniculata were estimated from site Kera of south Balaghat 1.2%. Lowest content of andrographolide in Andrographis paniculata were estimated from the site of Salhen north Balaghat region that is 0.02%. Conclusion:The content of this active ingredient in this plant varies with in the plant parts and with the geographical distribution.