Variation of usual interstitial pneumonia using HRCT in Scleroderma Patients

Abstract

Progressive Systemic Sclerosis or Scleroderma is a systemic inflammation marked by endothelial damaged, fibrosis, and inflammation in skin, joints, and visceral organs. Pulmonary hypertension and interstitial pulmonary disease (Ssc-ILD) are the most reported pulmonary complications in scleroderma patients. The pathogenesis of SSc- ILD is not well understood and the spectrum of SSc-ILD ranges from minimal lung involvement, which is often non-progressive, to severe illnesses. Usual Interstitial Pneumonia's (UIP) is one pattern of Ssc-ILD, marked in one-third of the patients with characteristic of honeycomb appearance and bronchiectasis. It is very important to determine the UIP based on radiology imaging especially with the presence of a poor prognosis in patients with UIP. This case report will discuss the importance of finding UIP-type ILD patterns based on HRCT in patients with scleroderma and different outcome.

Interstitial lung disease in Indonesian adult with systemic sclerotic: A rare case

“…Interstitial lung disease (ILD) is the most common form of SSc [ 2 ], and it is estimated that SSc-ILD is >80% of SSc cases [ 1 , 2 ]. In Indonesia, SSc-ILD is a rare case that until now has only been reported in two cities, namely Bandung and Jakarta [ 3 , 4 ]. Based on this description, we are interested in reporting the SSc-ILD in Indonesian adults.…”