Nonnegative matrix factorization (NMF) is a feature learning method that can achieve nonlinear dimensional approximate reduction with strong interpretation, and it is widely used in the field of tumor recognition. The objective function of the traditional NMF model is based on the Euclidean distance metric, and the performance of the model is easily affected by the noise. Moreover, traditional NMF is an unsupervised feature learning method that does not use the label information of the data. However, it would cause a waste of information without using label information and cannot learn the discriminative features in the data. Therefore, the supervised nonnegative matrix factorization model with fused correntropy (FCSNMF) is proposed in this paper. The FCSNMF model alleviates the effect of noise in the experimental data by fusing the Euclidean distance metric and the maximum correntropy metric. In addition, the label consistency regularization term is skillfully chosen to utilize the label information of the data to obtain discriminative features. The effectiveness of the FCSNMF model is verified by applying it to a gene expression profile dataset for tumor recognition.